GREP C00415

Selected compound(s)

C00415 7,8-Dihydrofolate

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.5.1.- : THF + NAD+ = 7,8-Dihydrofolate + NADH + H+
[Fig] 1.5.1.- : 7,8-Dihydrofolate + NAD+ = Folate + NADH + H+
[Fig] 1.5.1.- : 7,8-Dihydrofolate + NADPH + H+ = THF + NADP+
[Fig] 1.5.1.- : Folate + NADPH + H+ = 7,8-Dihydrofolate + NADP+
[Fig] 1.5.3.- : THF + O2 = 7,8-Dihydrofolate + H2O2
[Fig] 1.5.3.- : 7,8-Dihydrofolate + O2 = Folate + H2O2
[Fig] 1.5.4.- : 7,8-Dihydrofolate + 1,4-Dithiothreitol = THF + Oxidized dithiothreitol
[Fig] 1.5.4.- : Folate + 1,4-Dithiothreitol = 7,8-Dihydrofolate + Oxidized dithiothreitol
[Fig] 1.5.5.- : Folate + CoQH2 = 7,8-Dihydrofolate + CoQ
[Fig] 1.5.99.- : THF + FAD = 7,8-Dihydrofolate + FADH2
[Fig] 1.5.99.- : THF + Coenzyme F420 = 7,8-Dihydrofolate + Reduced coenzyme F420
[Fig] 1.5.99.- : 7,8-Dihydrofolate + FAD = Folate + FADH2
[Fig] 1.5.99.- : 7,8-Dihydrofolate + Coenzyme F420 = Folate + Reduced coenzyme F420
[Fig] 2.1.2.- : 10-Formyldihydrofolate + THF = 7,8-Dihydrofolate + 10-Formyl-THF
[Fig] 3.5.1.- : 7,8-Dihydrofolate + H2O = L-Glutamate + 7,8-Dihydropteroate
[Fig] 3.5.1.- : 10-Formyldihydrofolate + H2O = 7,8-Dihydrofolate + Formate
[Fig] 6.3.1.- : L-Glutamate + 7,8-Dihydropteroate + ATP = 7,8-Dihydrofolate + ADP + Orthophosphate
[Fig] 6.3.1.- : L-Glutamate + 7,8-Dihydropteroate + ATP = 7,8-Dihydrofolate + Diphosphate + 5'-AMP
[Fig] 6.3.4.- : 10-Formyldihydrofolate + ADP + Orthophosphate = 7,8-Dihydrofolate + Formate + ATP

Reported reactions

[Fig] EC 1.5.1.3 : 7,8-Dihydrofolate + NAD+ = Folate + NADH + H+
[Fig] EC 1.5.1.3 : 7,8-Dihydrofolate + NADP+ = Folate + NADPH + H+
[Fig] EC 2.1.1.45 : ATP + 7,8-Dihydropteroate + L-Glutamate = ADP + Orthophosphate + 7,8-Dihydrofolate
[Fig] EC 6.3.2.12 : ATP + 7,8-Dihydropteroate + L-Glutamate = ADP + Orthophosphate + 7,8-Dihydrofolate
[Fig] EC 6.3.2.17 : ATP + 7,8-Dihydropteroate + L-Glutamate = ADP + Orthophosphate + 7,8-Dihydrofolate
[Fig] EC 6.3.4.17 : ATP + Formate + 7,8-Dihydrofolate = ADP + Orthophosphate + 10-Formyldihydrofolate
[Fig] EC 2.1.1.45 : 2'-Deoxyuridine 5'-phosphate + 5,10-Methylene-THF = 7,8-Dihydrofolate + 5'-Thymidylic acid
[Fig] EC 1.5.1.3 : THF + NAD+ = 7,8-Dihydrofolate + NADH + H+
[Fig] EC 1.5.1.3 : THF + NADP+ = 7,8-Dihydrofolate + NADPH + H+
[Fig] EC 2.1.1.54 : 5,10-Methylene-THF + 2'-Deoxycytidine 5'-monophosphate = 7,8-Dihydrofolate + 5-Methyldeoxycytidine 5'-phosphate

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.