GREP C00270

Selected compound(s)

C00270 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.14.11.- : 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + O2 + 2-Ketoglutaric acid = N-Glycoloyl-neuraminate + CO2 + Butanedionic acid
[Fig] 1.14.13.- : N-Glycoloyl-neuraminate + H2O + NAD+ = 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + NADH + O2 + H+
[Fig] 1.14.13.- : N-Glycoloyl-neuraminate + H2O + NADP+ = 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + NADPH + O2 + H+
[Fig] 1.14.16.- : N-Glycoloyl-neuraminate + 6,7-Dihydrobiopterin + H2O = 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + O2
[Fig] 1.14.17.- : 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + Vitamin C + O2 = N-Glycoloyl-neuraminate + Dehydroascorbate + H2O
[Fig] 2.3.1.- : N-Acetyl-4-O-acetylneuraminate + CoA = 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + Acetyl-CoA
[Fig] 2.3.1.- : N-Acetyl-7-O-acetylneuraminate + CoA = 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + Acetyl-CoA
[Fig] 2.3.1.- : N-Acetyl-9-O-acetylneuraminate + CoA = 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + Acetyl-CoA
[Fig] 2.7.1.- : 5'-AMP + N-Acetylneuraminate 9-phosphate = ADP + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid
[Fig] 2.7.1.- : UMP + N-Acetylneuraminate 9-phosphate = UDP + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid
[Fig] 2.7.1.- : 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + ATP = N-Acetylneuraminate 9-phosphate + ADP
[Fig] 2.7.1.- : 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + UDP = N-Acetylneuraminate 9-phosphate + UMP
[Fig] 2.7.1.- : 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + Protein L-histidine = N-Acetylneuraminate 9-phosphate + Protein N(pai)-phosphohistidine
[Fig] 3.1.1.- : N-Acetyl-4-O-acetylneuraminate + H2O = 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + Acetate
[Fig] 3.1.1.- : N-Acetyl-7-O-acetylneuraminate + H2O = 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + Acetate
[Fig] 3.1.1.- : N-Acetyl-9-O-acetylneuraminate + H2O = 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + Acetate
[Fig] 3.1.3.- : N-Acetylneuraminate 9-phosphate + H2O = Orthophosphate + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid
[Fig] 3.1.3.- : N-Acetylneuraminate 9-phosphate + H2O = 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + Orthophosphate

Reported reactions

[Fig] EC 3.2.1.18 : D-Galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N- acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = GD1a + H2O
[Fig] EC 3.2.1.18 : Cerebroside + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = GM4 + H2O
[Fig] EC 3.2.1.18 : GM2 + H2O = GA2 + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid
[Fig] EC 3.2.1.18 : D-Galactosyl-1,4-beta-D-glucosylceramide + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = (N-Acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O
[Fig] EC 2.7.7.43 : CTP + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = Diphosphate + CMP-N-acetylneuraminate
[Fig] EC 3.2.1.18 : GT1b + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = GQ1b + H2O
[Fig] EC 3.2.1.18 : GT1b + H2O = GD1b + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid
[Fig] EC 3.2.1.18 : CDw17 + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = GM3; + H2O
[Fig] EC 3.2.1.18 : GT1b + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = GQ1 + H2O
[Fig] EC 3.2.1.18 : GT1b + H2O = GD1b + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid
[Fig] EC 1.14.18.2 : 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + 2 Ferrocytochrome b5 + O2 + 2 H+ = N-Glycoloyl-neuraminate + 2 Ferricytochrome b5 + H2O
[Fig] EC 2.5.1.56 : 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + Orthophosphate = 2-Acetamido-2-deoxy-D-mannose + PEP + H2O
[Fig] EC 3.1.3.29 : N-Acetylneuraminate 9-phosphate + H2O = 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + Orthophosphate
[Fig] EC 2.3.1.44 : Acetyl-CoA + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = CoA + N-Acetyl-4-O-acetylneuraminate
[Fig] EC 2.3.1.45 : Acetyl-CoA + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = CoA + N-Acetyl-7-O-acetylneuraminate
[Fig] EC 2.3.1.45 : Acetyl-CoA + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = CoA + N-Acetyl-9-O-acetylneuraminate
[Fig] EC 3.2.1.18 : GM1 + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = GD1a + H2O
[Fig] EC 3.2.1.18 : Galactosylceramide + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = GM4 + H2O
[Fig] EC 3.2.1.18 : GM2; + H2O = GA2 + 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid
[Fig] EC 3.1.1.53 : N-Acyl-O-acetylneuraminate + H2O = 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid + Acetate
[Fig] EC 4.1.3.3 : 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid = 2-Acetamido-2-deoxy-D-mannose + 2-Oxopropanoate

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.