GREP C00233

Selected compound(s)

C00233 2-Oxoisocaproate

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.2.1.- : 2-Oxoisocaproate + NADPH = 3-Methylbutanol + NADP+ + CO2
[Fig] 1.2.1.- : 2-Oxoisocaproate + NADPH = 3-Methylbutanol + NADP+ + CO2 + H+
[Fig] 1.2.1.- : 3-Methylbutanol + NAD+ + CO2 + H+ = 2-Oxoisocaproate + NADH
[Fig] 1.2.1.- : 3-Methylbutanol + NAD+ + CO2 = 2-Oxoisocaproate + NADH
[Fig] 1.4.1.- : L-Leucine + H2O + NAD+ = 2-Oxoisocaproate + NADH + Ammonia
[Fig] 1.4.1.- : L-Leucine + H2O + NAD+ = 2-Oxoisocaproate + NADH + Ammonia + H+
[Fig] 1.4.1.- : L-Leucine + H2O + NAD+ = 2-Oxoisocaproate + NADH + H+ + Ammonia
[Fig] 1.4.1.- : L-Leucine + H2O + NADP+ = 2-Oxoisocaproate + NADPH + Ammonia
[Fig] 1.4.1.- : L-Leucine + H2O + NADP+ = 2-Oxoisocaproate + NADPH + Ammonia + H+
[Fig] 1.4.1.- : L-Leucine + H2O + NADP+ = 2-Oxoisocaproate + NADPH + H+ + Ammonia
[Fig] 1.4.1.- : L-Leucine + NAD+ + H2O = 2-Oxoisocaproate + Ammonia + NADH
[Fig] 1.4.1.- : L-Leucine + NAD+ + H2O = 2-Oxoisocaproate + Ammonia + NADH + H+
[Fig] 1.4.1.- : L-Leucine + NADP+ + H2O = 2-Oxoisocaproate + Ammonia + NADPH
[Fig] 1.4.1.- : L-Leucine + NADP+ + H2O = 2-Oxoisocaproate + Ammonia + NADPH + H+
[Fig] 1.4.3.- : L-Leucine + H2O + O2 = 2-Oxoisocaproate + Ammonia + H2O2
[Fig] 2.6.1.- : L-Leucine + Pyridoxal 5'-phosphate = 2-Oxoisocaproate + Pyridoxamine 5'-phosphate
[Fig] 2.6.1.- : 2-Oxoisocaproate + L-Glutamate = L-Leucine + 2-Ketoglutaric acid

Reported reactions

[Fig] EC 1.4.1.9 : L-Leucine + H2O + NAD+ = 2-Oxoisocaproate + Ammonia + NADH
[Fig] EC 2.6.1.6 : L-Leucine + 2-Ketoglutaric acid = 2-Oxoisocaproate + L-Glutamate
[Fig] EC 2.6.1.42 : L-Leucine + 2-Ketoglutaric acid = 2-Oxoisocaproate + L-Glutamate
[Fig] EC 1.2.1.25 : 2-Oxoisocaproate + CoA + NAD+ = 3-Methylbutanoyl-CoA + CO2 + NADH
[Fig] EC 1.2.4.4 : 2-Oxoisocaproate + Lipoamide = S-(3-Methylbutanoyl)-dihydrolipoamide + CO2

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.