GREP C00143

Selected compound(s)

C00143 5,10-Methylene-THF

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.5.1.- : 5,10-Methylene-THF + NAD+ = 5,10-Methenyltetrahydrofolate + NADH
[Fig] 1.5.1.- : 5,10-Methylene-THF + NAD+ = 5,10-Methenyltetrahydrofolate + NADH + H+
[Fig] 1.5.1.- : 5,10-Methenyltetrahydrofolate + NADPH + H+ = 5,10-Methylene-THF + NADP+
[Fig] 1.5.1.- : 5,10-Methenyltetrahydrofolate + NADPH = 5,10-Methylene-THF + NADP+
[Fig] 1.5.3.- : 5,10-Methylene-THF + O2 = 5,10-Methenyltetrahydrofolate + H2O2
[Fig] 1.5.4.- : 5,10-Methenyltetrahydrofolate + 1,4-Dithiothreitol = 5,10-Methylene-THF + Oxidized dithiothreitol
[Fig] 1.5.99.- : 5,10-Methylene-THF + FAD = 5,10-Methenyltetrahydrofolate + FADH2
[Fig] 2.1.2.- : (13aS)-5,8,13,13a-tetrahydro-3,10-dimethoxy-6H- dibenzo[a,g]quinolizine-2,9-diol + THF = (S)-Norreticuline + 5,10-Methylene-THF
[Fig] 2.1.2.- : Aconitane-4-methanol, 20-ethyl-7,8-(methylenebis(oxy))-, 1,6,14,16-tetramethoxy-2-(3-methyl-2,5-dioxo-1- pyrrolidinyl)benzoate(ester), (1-alpha,6-beta,14-alpha,16-beta)- + THF = Methyllycaconitine + 5,10-Methylene-THF
[Fig] 2.1.2.- : Aconitane-4-methanol, 20-ethyl-7,8-(methylenebis(oxy))-, 1,6,14,16-tetramethoxy-2-(3-methyl-2,5-dioxo-1- pyrrolidinyl)benzoate(ester), (1-alpha,6-beta,14-alpha,16-beta)- + THF = Methyllycaconitine + 5,10-Methylene-THF

Reported reactions

[Fig] EC 2.1.2.1 : 5,10-Methylene-THF + Glycine + H2O = THF + L-Serine
[Fig] EC 2.1.2.10 : THF + S-Aminomethyldihydrolipoylprotein = 5,10-Methylene-THF + Ammonia + Dihydrolipoylprotein
[Fig] EC 2.1.2.8 : 5,10-Methylene-THF + H2O + 2'-Deoxycytidine 5'-monophosphate = THF + 2'-Deoxy-5-hydroxymethylcytidine 5'-phosphate
[Fig] EC 1.5.1.5 : 5,10-Methylene-THF + NADP+ = 5,10-Methenyltetrahydrofolate + NADPH
[Fig] EC 2.1.2.10 : Glycine + THF + NAD+ = 5,10-Methylene-THF + Ammonia + CO2 + NADH + H+
[Fig] EC 1.5.1.20 : 5,10-Methylene-THF + FADH2 = 5-Methyltetrahydrofolate + FAD
[Fig] EC 1.5.1.20 : 5-Methyltetrahydrofolate + NADP+ = 5,10-Methylene-THF + NADPH + H+
[Fig] EC 2.1.2.7 : 5,10-Methylene-THF + D-Alanine + H2O = THF + 2-Methylserine
[Fig] EC 2.1.2.11 : 5,10-Methylene-THF + alpha-Ketovaline + H2O = THF + 2-Dehydropantoate
[Fig] EC 2.1.1.74 : 5,10-Methylene-THF + tRNA UpsiC + FADH2 = THF + tRNA TpsiC + FAD
[Fig] EC 2.1.1.45 : 2'-Deoxyuridine 5'-phosphate + 5,10-Methylene-THF = 7,8-Dihydrofolate + 5'-Thymidylic acid
[Fig] EC 2.1.1.148 : 5,10-Methylene-THF + 2'-Deoxyuridine 5'-phosphate + FADH2 = THF + 5'-Thymidylic acid + FAD
[Fig] EC 2.1.1.54 : 5,10-Methylene-THF + 2'-Deoxycytidine 5'-monophosphate = 7,8-Dihydrofolate + 5-Methyldeoxycytidine 5'-phosphate
[Fig] EC 1.7.7.- : 5,10-Methylene-THF + 2 Reduced ferredoxin = 5-Methyltetrahydrofolate + 2 Oxidized ferredoxin
[Fig] EC 1.5.1.15 : 5,10-Methylene-THF + NAD+ = 5,10-Methenyltetrahydrofolate + NADH

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.