GREP C00141

Selected compound(s)

C00141 alpha-Ketovaline

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : alpha-Ketovaline + NADPH + CO2 + H+ = (R)-3,3-Dimethylmalate + NADP+
[Fig] 1.1.1.- : alpha-Ketovaline + NADPH + CO2 = (R)-3,3-Dimethylmalate + NADP+
[Fig] 1.1.1.- : (R)-3,3-Dimethylmalate + NAD+ = alpha-Ketovaline + NADH + CO2 + H+
[Fig] 1.1.1.84 1.1.1.- : (R)-3,3-Dimethylmalate + NAD+ = alpha-Ketovaline + NADH + CO2
[Fig] 1.4.1.- : L-Valine + H2O + NAD+ = alpha-Ketovaline + NADH + Ammonia
[Fig] 1.4.1.- : L-Valine + H2O + NAD+ = alpha-Ketovaline + NADH + Ammonia + H+
[Fig] 1.4.1.- : L-Valine + H2O + NAD+ = alpha-Ketovaline + NADH + H+ + Ammonia
[Fig] 1.4.1.- : L-Valine + H2O + NADP+ = alpha-Ketovaline + NADPH + Ammonia
[Fig] 1.4.1.- : L-Valine + H2O + NADP+ = alpha-Ketovaline + NADPH + Ammonia + H+
[Fig] 1.4.1.- : L-Valine + H2O + NADP+ = alpha-Ketovaline + NADPH + H+ + Ammonia
[Fig] 1.4.1.- : L-Valine + NAD+ + H2O = alpha-Ketovaline + Ammonia + NADH
[Fig] 1.4.1.- : L-Valine + NAD+ + H2O = alpha-Ketovaline + Ammonia + NADH + H+
[Fig] 1.4.1.- : L-Valine + NADP+ + H2O = alpha-Ketovaline + Ammonia + NADPH
[Fig] 1.4.1.- : L-Valine + NADP+ + H2O = alpha-Ketovaline + Ammonia + NADPH + H+
[Fig] 1.4.3.- : L-Valine + H2O + O2 = alpha-Ketovaline + Ammonia + H2O2
[Fig] 2.6.1.- : alpha-Ketovaline + L-Glutamate = L-Valine + 2-Ketoglutaric acid
[Fig] 2.6.1.- : L-Valine + Pyridoxal 5'-phosphate = alpha-Ketovaline + Pyridoxamine 5'-phosphate
[Fig] 4.1.2.- : alpha-Ketovaline + Formaldehyde = 2-Dehydropantoate
[Fig] 5.4.99.- : 2-Oxopentanoate = alpha-Ketovaline

Reported reactions

[Fig] EC 2.1.2.11 : 5,10-Methylene-THF + alpha-Ketovaline + H2O = THF + 2-Dehydropantoate
[Fig] EC 4.2.1.9 : 2,3-Dihydroxy-3-methylbutanoate = alpha-Ketovaline + H2O
[Fig] EC 4.2.1.9 : (R)-2,3-Dihydroxy-3-methylbutanoate = alpha-Ketovaline + H2O
[Fig] EC 1.4.1.9 : L-Valine + H2O + NAD+ = alpha-Ketovaline + Ammonia + NADH
[Fig] EC 1.2.1.25 : alpha-Ketovaline + CoA + NAD+ = 2-Methylpropanoyl-CoA + CO2 + NADH
[Fig] EC 1.1.1.84 : NADH + (R)-3,3-Dimethylmalate + NAD+ = alpha-Ketovaline + CO2 + NADH
[Fig] EC 1.4.1.8 : L-Valine + NADP+ + H2O = alpha-Ketovaline + Ammonia + NADPH
[Fig] EC 2.3.3.13 : 2-Isopropylmalate + CoA = Acetyl-CoA + alpha-Ketovaline + H2O
[Fig] EC 2.6.1.6 : L-Valine + 2-Ketoglutaric acid = alpha-Ketovaline + L-Glutamate
[Fig] EC 2.6.1.42 : L-Valine + 2-Ketoglutaric acid = alpha-Ketovaline + L-Glutamate
[Fig] EC 2.6.1.66 : L-Valine + 2-Oxopropanoate = alpha-Ketovaline + L-Alanine
[Fig] EC 4.1.2.12 : 2-Dehydropantoate = alpha-Ketovaline + Formaldehyde
[Fig] EC 1.2.4.4 : alpha-Ketovaline + Lipoamide = S-(2-Methylpropanoyl)-dihydrolipoamide + CO2
[Fig] EC 2.3.1.- : alpha-Ketovaline + Lipoamide = S-(2-Methylpropanoyl)-dihydrolipoamide + CO2
[Fig] EC 2.6.1.32 : L-Valine + (3S)-3-Methyl-2-oxopentanoate = alpha-Ketovaline + L-Isoleucine

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.