GREP C00123

Selected compound(s)

C00123 L-Leucine

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.4.1.- : L-Leucine + H2O + NAD+ = 2-Oxoisocaproate + NADH + Ammonia
[Fig] 1.4.1.- : L-Leucine + H2O + NAD+ = 2-Oxoisocaproate + NADH + Ammonia + H+
[Fig] 1.4.1.- : L-Leucine + H2O + NAD+ = 2-Oxoisocaproate + NADH + H+ + Ammonia
[Fig] 1.4.1.- : L-Leucine + H2O + NADP+ = 2-Oxoisocaproate + NADPH + Ammonia
[Fig] 1.4.1.- : L-Leucine + H2O + NADP+ = 2-Oxoisocaproate + NADPH + Ammonia + H+
[Fig] 1.4.1.- : L-Leucine + H2O + NADP+ = 2-Oxoisocaproate + NADPH + H+ + Ammonia
[Fig] 1.4.1.- : L-Leucine + NAD+ + H2O = 2-Oxoisocaproate + Ammonia + NADH
[Fig] 1.4.1.- : L-Leucine + NAD+ + H2O = 2-Oxoisocaproate + Ammonia + NADH + H+
[Fig] 1.4.1.- : L-Leucine + NADP+ + H2O = 2-Oxoisocaproate + Ammonia + NADPH
[Fig] 1.4.1.- : L-Leucine + NADP+ + H2O = 2-Oxoisocaproate + Ammonia + NADPH + H+
[Fig] 1.4.3.- : L-Leucine + H2O + O2 = 2-Oxoisocaproate + Ammonia + H2O2
[Fig] 2.3.1.- : L-Leucine + Acetyl phosphate = N-Acetyl-L-leucine + Orthophosphate
[Fig] 2.3.1.- : N-Acetyl-L-leucine + CoA = L-Leucine + Acetyl-CoA
[Fig] 2.6.1.- : L-Leucine + Pyridoxal 5'-phosphate = 2-Oxoisocaproate + Pyridoxamine 5'-phosphate
[Fig] 2.6.1.- : 2-Oxoisocaproate + L-Glutamate = L-Leucine + 2-Ketoglutaric acid
[Fig] 3.2.1.- : L-Leucyl-tRNA + H2O = L-Leucine + tRNA(Gln)
[Fig] 3.2.1.- : L-Leucyl-tRNA + H2O = tRNA(Leu) + L-Leucine
[Fig] 3.5.1.- : N-Acetyl-L-leucine + H2O = L-Leucine + Acetate
[Fig] 5.-.-.- : L-Leucine = D-2-Amino-4-methylvaleric acid

Reported reactions

[Fig] EC 1.4.1.9 : L-Leucine + H2O + NAD+ = 2-Oxoisocaproate + Ammonia + NADH
[Fig] EC 2.3.1.66 : Acetyl-CoA + L-Leucine = CoA + N-Acetyl-L-leucine
[Fig] EC 6.1.1.4 : ATP + L-Leucine + tRNA(Leu) = 5'-AMP + Diphosphate + L-Leucyl-tRNA
[Fig] EC 2.6.1.6 : L-Leucine + 2-Ketoglutaric acid = 2-Oxoisocaproate + L-Glutamate
[Fig] EC 2.6.1.42 : L-Leucine + 2-Ketoglutaric acid = 2-Oxoisocaproate + L-Glutamate
[Fig] EC 5.4.3.7 : L-Leucine = (3R)-beta-2-Amino-4-methylvaleric acid
[Fig] EC 3.5.1.64 : N(alpha)-Benzyloxycarbonyl-L-leucine + H2O = Benzenemethanol + CO2 + L-Leucine

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.