GREP C00090

Selected compound(s)

C00090 1,2-Benzenediol

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 1,2-Benzenediol + NAD+ = 1,2-Benzoquinone + NADH + H+
[Fig] 1.1.1.- : 1,2-Benzoquinone + NADPH + H+ = 1,2-Benzenediol + NADP+
[Fig] 1.1.3.- : 1,2-Benzenediol + O2 = 1,2-Benzoquinone + H2O2
[Fig] 1.1.4.- : 1,2-Benzoquinone + 1,4-Dithiothreitol = 1,2-Benzenediol + Oxidized dithiothreitol
[Fig] 1.1.5.- : 1,2-Benzoquinone + CoQH2 = 1,2-Benzenediol + CoQ
[Fig] 1.1.99.- : 1,2-Benzenediol + FAD = 1,2-Benzoquinone + FADH2
[Fig] 1.1.99.- : 1,2-Benzenediol + Coenzyme F420 = 1,2-Benzoquinone + Reduced coenzyme F420
[Fig] 1.2.1.- : 1,2-Benzenediol + NADH + CO2 = 1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+
[Fig] 1.2.1.- : 1,2-Benzenediol + NADH + CO2 = 1,6-Dihydroxy-cis-2,4-cyclohexadiene-1-carboxylic acid + NAD+
[Fig] 1.2.1.- : 1,2-Benzenediol + NADPH + CO2 = 1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NADP+
[Fig] 1.2.1.- : 1,2-Benzenediol + NADPH + CO2 = 1,6-Dihydroxy-cis-2,4-cyclohexadiene-1-carboxylic acid + NADP+
[Fig] 1.3.1.- : 1,2-Benzenediol + NADPH + H+ = cis-1,2-Dihydrobenzene-1,2-diol + NADP+
[Fig] 1.3.1.- : 1,2-Benzenediol + NADPH + H+ = trans-1,2-Dihydrobenzene-1,2-diol + NADP+
[Fig] 1.3.1.- : cis-1,2-Dihydrobenzene-1,2-diol + NAD+ = 1,2-Benzenediol + NADH + H+
[Fig] 1.3.1.- : trans-1,2-Dihydrobenzene-1,2-diol + NAD+ = 1,2-Benzenediol + NADH + H+
[Fig] 1.3.3.- : cis-1,2-Dihydrobenzene-1,2-diol + O2 = 1,2-Benzenediol + H2O2
[Fig] 1.3.3.- : trans-1,2-Dihydrobenzene-1,2-diol + O2 = 1,2-Benzenediol + H2O2
[Fig] 1.3.4.- : 1,2-Benzenediol + 1,4-Dithiothreitol = cis-1,2-Dihydrobenzene-1,2-diol + Oxidized dithiothreitol
[Fig] 1.3.4.- : 1,2-Benzenediol + 1,4-Dithiothreitol = trans-1,2-Dihydrobenzene-1,2-diol + Oxidized dithiothreitol
[Fig] 1.3.5.- : 1,2-Benzenediol + CoQH2 = cis-1,2-Dihydrobenzene-1,2-diol + CoQ
[Fig] 1.3.5.- : 1,2-Benzenediol + CoQH2 = trans-1,2-Dihydrobenzene-1,2-diol + CoQ
[Fig] 1.3.99.- : cis-1,2-Dihydrobenzene-1,2-diol + FAD = 1,2-Benzenediol + FADH2
[Fig] 1.3.99.- : cis-1,2-Dihydrobenzene-1,2-diol + Coenzyme F420 = 1,2-Benzenediol + Reduced coenzyme F420
[Fig] 1.3.99.- : trans-1,2-Dihydrobenzene-1,2-diol + FAD = 1,2-Benzenediol + FADH2
[Fig] 1.3.99.- : trans-1,2-Dihydrobenzene-1,2-diol + Coenzyme F420 = 1,2-Benzenediol + Reduced coenzyme F420
[Fig] 1.13.11.- : 2-Hydroxyphenylpropanoate + O2 = 3-Oxopropanoate + 1,2-Benzenediol
[Fig] 1.14.13.- : 1,2-Benzenediol + H2O + NAD+ = Phenol + NADH + O2 + H+
[Fig] 1.14.13.- : 1,2-Benzenediol + H2O + NAD+ = Phenol + NADH + O2 + H+
[Fig] 1.14.13.- : 1,2-Benzenediol + H2O + NADP+ = Phenol + NADPH + O2 + H+
[Fig] 1.14.13.- : 1,2-Benzenediol + H2O + NADP+ = Phenol + NADPH + O2 + H+
[Fig] 1.14.13.- : 1,2,3-Benzenetriol + H2O + NAD+ = 1,2-Benzenediol + NADH + O2 + H+
[Fig] 1.14.13.- : 1,2,3-Benzenetriol + H2O + NADP+ = 1,2-Benzenediol + NADPH + O2 + H+
[Fig] 2.1.1.- : 1,2-Benzenediol + S-Adenosyl-L-methionine = Catechol monomethyl ether + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : 1,2-Benzenediol + S-Adenosyl-L-methionine = Catechol monomethyl ether + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.1.- : 1,2-Benzenediol + S-Adenosyl-L-methionine = 1,2-Dihydroxy-4-methylbenzene + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : 1,2-Benzenediol + S-Adenosyl-L-methionine = 1,2-Dihydroxy-4-methylbenzene + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.2.- : 2,3-Dihydroxybenzoate + THF = 1,2-Benzenediol + 10-Formyl-THF
[Fig] 2.1.2.- : 3,4-Dihydroxybenzoate + THF = 1,2-Benzenediol + 10-Formyl-THF
[Fig] 2.3.1.- : 3',4'-Dihydroxyacetophenone + CoA = 1,2-Benzenediol + Acetyl-CoA
[Fig] 2.5.1.- : Orthophosphate + 3,4-Dihydroxy-trans-cinnamate = PEP + 1,2-Benzenediol
[Fig] 2.5.1.- : Orthophosphate + 2-Hydroxyphenylpropanoate = Propanoyl phosphate + 1,2-Benzenediol
[Fig] 3.1.1.- : 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate + H2O = 1,2-Benzenediol + 2-Hydroxymuconate
[Fig] 3.3.2.- : Catechol monomethyl ether + H2O = 1,2-Benzenediol + Methanol
[Fig] 3.3.2.- : 1,2-Dihydroxy-4-methylbenzene + H2O = 1,2-Benzenediol + Methanol
[Fig] 3.7.1.- : 2,3-Dihydroxybenzoate + H2O = 1,2-Benzenediol + Formate
[Fig] 3.7.1.- : 3,4-Dihydroxybenzoate + H2O = 1,2-Benzenediol + Formate
[Fig] 3.7.1.- : Caffeoyl-CoA + H2O = 1,2-Benzenediol + 3-Oxopropionyl-CoA
[Fig] 3.7.1.- : 3,4-Dihydroxy-L-phenylalanine + H2O = 1,2-Benzenediol + D-Serine
[Fig] 3.7.1.- : 3,4-Dihydroxy-trans-cinnamate + H2O = 3-Oxopropanoate + 1,2-Benzenediol
[Fig] 3.7.1.- : 2-Hydroxyphenylpropanoate + H2O = Propanoate + 1,2-Benzenediol
[Fig] 3.7.1.- : 3',4'-Dihydroxyacetophenone + H2O = 1,2-Benzenediol + Acetate
[Fig] 4.1.1.- : 1,2-Benzenediol + CO2 = 2,3-Dihydroxybenzoate
[Fig] 4.1.1.- : 1,2-Benzenediol + CO2 = 3,4-Dihydroxybenzoate
[Fig] 5.4.4.- : 1,4-Benzenediol = 1,2-Benzenediol
[Fig] 5.4.4.- : 1,3-Benzenediol = 1,2-Benzenediol
[Fig] 6.4.1.- : 1,2-Benzenediol + ATP + Acid carbonate = 2,3-Dihydroxybenzoate + ADP + Orthophosphate
[Fig] 6.4.1.- : 1,2-Benzenediol + ATP + Acid carbonate = 3,4-Dihydroxybenzoate + ADP + Orthophosphate
[Fig] 6.4.1.- : 1,2-Benzenediol + D-Serine + ATP = 3,4-Dihydroxy-L-phenylalanine + ADP + Orthophosphate
[Fig] 6.4.1.- : 1,2-Benzenediol + D-Serine + ATP = 3,4-Dihydroxy-L-phenylalanine + Diphosphate + 5'-AMP
[Fig] 6.4.1.- : 1,2-Benzenediol + 3-Oxopropionyl-CoA + ATP = Caffeoyl-CoA + ADP + Orthophosphate
[Fig] 6.4.1.- : 1,2-Benzenediol + 3-Oxopropionyl-CoA + ATP = Caffeoyl-CoA + Diphosphate + 5'-AMP
[Fig] 6.4.1.- : Propanoate + 1,2-Benzenediol + ATP = 2-Hydroxyphenylpropanoate + ADP + Orthophosphate
[Fig] 6.4.1.- : Propanoate + 1,2-Benzenediol + ATP = 2-Hydroxyphenylpropanoate + Diphosphate + 5'-AMP
[Fig] 6.4.1.- : 2,3-Dihydroxybenzoate + ADP + Orthophosphate = 1,2-Benzenediol + Formate + ATP
[Fig] 6.4.1.- : 3-Oxopropanoate + 1,2-Benzenediol + ATP = 3,4-Dihydroxy-trans-cinnamate + ADP + Orthophosphate
[Fig] 6.4.1.- : 3-Oxopropanoate + 1,2-Benzenediol + ATP = 3,4-Dihydroxy-trans-cinnamate + Diphosphate + 5'-AMP
[Fig] 6.4.1.- : 3,4-Dihydroxybenzoate + ADP + Orthophosphate = 1,2-Benzenediol + Formate + ATP

Reported reactions

[Fig] EC 1.3.1.19 : cis-1,2-Dihydrobenzene-1,2-diol + NAD+ = 1,2-Benzenediol + NADH
[Fig] EC 1.3.1.25 : 1,6-Dihydroxy-cis-2,4-cyclohexadiene-1-carboxylic acid + NAD+ = 1,2-Benzenediol + NADH + CO2
[Fig] EC 1.3.1.20 : trans-1,2-Dihydrobenzene-1,2-diol + NADP+ = 1,2-Benzenediol + NADPH
[Fig] EC 1.14.13.7 : Phenol + O2 + NADPH = 1,2-Benzenediol + NADP+ + H2O
[Fig] EC 1.13.11.2 : 1,2-Benzenediol + O2 = 2-Hydroxymuconate semialdehyde
[Fig] EC 1.13.11.1 : 1,2-Benzenediol + O2 = cis,cis-2,4-Hexadienedioic acid
[Fig] EC 1.14.13.1 : Salicylate + O2 + NADH = 1,2-Benzenediol + CO2 + NAD+ + H2O
[Fig] EC 1.14.12.10 : Benzoate + O2 + NADH = 1,2-Benzenediol + CO2 + NAD+
[Fig] EC 1.1.3.14 : 4 1,2-Benzenediol + 3 O2 = 6 H2O + 2 Dibenzo[1,4]dioxin-2,3-dione
[Fig] EC 1.3.1.25 : 1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ = 1,2-Benzenediol + CO2 + NADH
[Fig] EC 4.1.1.46 : 2,3-Dihydroxybenzoate = 1,2-Benzenediol + CO2
[Fig] EC 4.1.1.63 : 3,4-Dihydroxybenzoate = 1,2-Benzenediol + CO2
[Fig] EC 1.14.12.1 : Vitamin L1 + O2 + NADH + H+ = 1,2-Benzenediol + Ammonia + CO2 + NAD+
[Fig] EC 1.14.12.1 : Vitamin L1 + O2 + NADPH + H+ = 1,2-Benzenediol + Ammonia + CO2 + NADP+
[Fig] EC 2.1.1.6 : S-Adenosyl-L-methionine + 1,2-Benzenediol = S-Adenosyl-L-homocysteine + Catechol monomethyl ether
[Fig] EC 1.14.13.31 : 2-Nitrophenol + O2 + NADPH = 1,2-Benzenediol + Nitrite + NADP+ + H2O
[Fig] EC 1.14.12.13 : 2-Chlorobenzoate + O2 + NADH + H+ = Chloride + 1,2-Benzenediol + NAD+ + CO2
[Fig] EC 3.7.1.8 : 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate + H2O = 2-Hydroxymuconate + 1,2-Benzenediol
[Fig] EC 1.10.3.1 : O2 + 2 1,2-Benzenediol = 2 1,2-Benzoquinone + 2 H2O

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.