GREP C00083

Selected compound(s)

C00083 Malonyl-CoA

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 3-Hydroxyisobutyryl coemzyme A + H2O + 2 NAD+ = Malonyl-CoA + 2 NADH + 2 H+
[Fig] 1.1.1.- : 3-Hydroxyisobutyryl coemzyme A + H2O + 2 NADP+ = Malonyl-CoA + 2 NADPH + 2 H+
[Fig] 1.1.1.- : 3-Hydroxyisobutyryl coemzyme A + H2O + NAD+ = Malonyl-CoA + NADH + H+
[Fig] 1.1.1.- : 3-Hydroxyisobutyryl coemzyme A + H2O + NADP+ = Malonyl-CoA + NADPH + H+
[Fig] 1.1.4.- : 3-Hydroxyisobutyryl coemzyme A + H2O + Oxidized dithiothreitol = Malonyl-CoA + 1,4-Dithiothreitol
[Fig] 1.2.1.- : 3-Oxopropionyl-CoA + H2O + NAD+ = Malonyl-CoA + NADH + H+
[Fig] 1.2.1.- : 3-Oxopropionyl-CoA + H2O + NADP+ = Malonyl-CoA + NADPH + H+
[Fig] 1.2.3.- : 3-Oxopropionyl-CoA + H2O + O2 = Malonyl-CoA + H2O2
[Fig] 2.1.1.- : Malonyl-CoA + S-Adenosyl-L-methionine = (S)-2-Methyl-3-oxopropanoyl-CoA + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : Malonyl-CoA + S-Adenosyl-L-methionine = (S)-2-Methyl-3-oxopropanoyl-CoA + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.1.- : Malonyl-CoA + S-Adenosyl-L-methionine = (R)-2-Methyl-3-oxopropanoyl-CoA + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : Malonyl-CoA + S-Adenosyl-L-methionine = (R)-2-Methyl-3-oxopropanoyl-CoA + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.1.- : Malonyl-CoA + S-Adenosyl-L-methionine = 2-Methylmalonyl-CoA + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : Malonyl-CoA + S-Adenosyl-L-methionine = 2-Methylmalonyl-CoA + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.2.- : Malonyl-CoA + THF = Acetyl-CoA + 10-Formyl-THF
[Fig] 2.3.1.- : CoA + 4'''-Demalonylsalvianin = Malonyl-CoA + Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside
[Fig] 2.3.1.- : 7-(beta-D-Glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1- benzopyran-4-one + Malonyl-CoA = Apigenin 7-(6''-malonylglucoside) + CoA
[Fig] 3.1.2.- : Malonyl-CoA + H2O = CoA + Dicarboxylate
[Fig] 3.1.2.- : Malonyl-CoA + H2O = Malonate + CoA
[Fig] 3.3.2.- : (S)-2-Methyl-3-oxopropanoyl-CoA + H2O = Malonyl-CoA + Methanol
[Fig] 3.3.2.- : (R)-2-Methyl-3-oxopropanoyl-CoA + H2O = Malonyl-CoA + Methanol
[Fig] 3.3.2.- : 2-Methylmalonyl-CoA + H2O = Malonyl-CoA + Methanol
[Fig] 3.5.1.- : Malonamoyl-CoA + H2O = Malonyl-CoA + Ammonia
[Fig] 3.7.1.- : Malonyl-CoA + H2O = Acetyl-CoA + Formate
[Fig] 4.1.1.- : Acetyl-CoA + CO2 = Malonyl-CoA
[Fig] 5.-.-.- : Malonyl-CoA = omega-Carboxyacyl-CoA
[Fig] 6.2.1.- : CoA + Dicarboxylate + ATP = Malonyl-CoA + ADP + Orthophosphate
[Fig] 6.2.1.- : CoA + Dicarboxylate + ATP = Malonyl-CoA + Diphosphate + 5'-AMP
[Fig] 6.2.1.- : Malonate + CoA + ATP = Malonyl-CoA + ADP + Orthophosphate
[Fig] 6.2.1.- : Malonate + CoA + ATP = Malonyl-CoA + Diphosphate + 5'-AMP
[Fig] 6.3.4.- : Malonyl-CoA + ATP + Ammonia = Malonamoyl-CoA + ADP + Orthophosphate
[Fig] 6.3.4.- : Malonyl-CoA + ATP + Ammonia = Malonamoyl-CoA + Diphosphate + 5'-AMP
[Fig] 6.4.1.- : Acetyl-CoA + ATP + Acid carbonate = Malonyl-CoA + ADP + Orthophosphate
[Fig] 6.4.1.- : Malonyl-CoA + ADP + Orthophosphate = Acetyl-CoA + Formate + ATP

Reported reactions

[Fig] EC 2.3.1.115 : Biochanin A-beta-D-glucoside + Malonyl-CoA = Biochanin A 7-O-(6-O-malonyl-beta-D-glucoside) + CoA
[Fig] EC 2.3.1.116 : 2-(3,4-Dihidroxyphenyl)-3-(beta-D-glucofuranosyloxy)-5,7-dihydroxy- 4H-1-benzopyran-4-one + Malonyl-CoA = Quercetin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA
[Fig] EC 2.3.1.172 : Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + Malonyl-CoA = 4'''-Demalonylsalvianin + CoA
[Fig] EC 2.3.1.115 : Malonyl-CoA + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'- trihydroxyflavone = CoA + Malonylapiin
[Fig] EC 2.3.1.151 : 3 Malonyl-CoA + 3-Hydroxybenzoyl-CoA = 4 CoA + 2,3',4,6-Tetrahydroxybenzophenone + 3 CO2
[Fig] EC 2.3.1.115 : 7-(beta-D-Glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1- benzopyran-4-one + Malonyl-CoA = Apigenin 7-(6''-malonylglucoside) + CoA
[Fig] EC 2.3.1.171 : Pelargonidin 3-O-glucoside + Malonyl-CoA = Pelargonidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA
[Fig] EC 2.3.1.86 : Acetyl-CoA + n Malonyl-CoA + 2n NADPH + 2n H+ = Long-chain acyl-CoA + n CoA + n CO2 + 2n NADP+ + n H2O
[Fig] EC 2.3.1.156 : 3-Methylbutanoyl-CoA + 3 Malonyl-CoA = 4 CoA + 3 CO2 + 3-Methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one
[Fig] EC 2.3.1.39 : Malonyl-CoA + ACP = CoA + Malonyl-[acyl-carrier protein]
[Fig] EC 2.3.1.85 : Malonyl-CoA + ACP = CoA + Malonyl-[acyl-carrier protein]
[Fig] EC 2.3.1.86 : Malonyl-CoA + ACP = CoA + Malonyl-[acyl-carrier protein]
[Fig] EC 2.1.3.1 : Malonyl-CoA + 2-Oxopropanoate = Acetyl-CoA + keto-Oxaloacetate
[Fig] EC 2.3.1.146 : 3 Malonyl-CoA + Cinnamoyl-CoA = 4 CoA + Pinosylvin + 4 CO2
[Fig] EC 2.3.1.115 : Malonyl-CoA + Biochanin A-beta-D-glucoside = CoA + 6''-O-Malonyl-biochanin A-beta-D-glucoside
[Fig] EC 2.3.1.116 : Malonyl-CoA + Flavonol 3-O-beta-D-glucoside = CoA + Malonyl-flavonol 3-O-beta-D-glucoside
[Fig] EC 2.3.1.171 : Cyanidin 3-O-glucoside + Malonyl-CoA = Cyanidin 3-O-(6'-O-malonylglucoside) + CoA
[Fig] EC 2.3.1.85 : Acetyl-CoA + n Malonyl-CoA + 2n NADPH = Higher fatty acid + n CO2 + 2n NADP+ + (n+1) CoA
[Fig] EC 2.3.1.74 : 4-Coumaroyl-CoA + 3 Malonyl-CoA = 2'4'6'4-Tetrahydroxychalcone + 4 CoA + 3 CO2
[Fig] EC 2.3.1.95 : 3 Malonyl-CoA + 4-Coumaroyl-CoA = 4 CoA + 3,4',5-Trihydroxystilbene + 4 CO2
[Fig] EC 2.3.1.112 : Malonyl-CoA + D-Tryptophan = CoA + N2-Malonyl-D-tryptophan
[Fig] EC 2.3.1.151 : 3 Malonyl-CoA + Benzoyl-CoA = 4 CoA + 2,4,6-Trihydroxybenzophenone + 3 CO2
[Fig] EC 2.3.1.119 : Stearoyl-CoA + Malonyl-CoA + 2 NADH + 2 H+ = Eicosanoyl-CoA + CO2 + 2 NAD+ + CoA + H2O
[Fig] EC 2.3.1.119 : Stearoyl-CoA + Malonyl-CoA + 2 NADPH + 2 H+ = Eicosanoyl-CoA + CO2 + 2 NADP+ + CoA + H2O
[Fig] EC 4.1.1.9 : Malonyl-CoA = Acetyl-CoA + CO2
[Fig] EC 2.3.1.113 : Malonyl-CoA + Vitamin L1 = CoA + N-Malonylanthranilate
[Fig] EC 6.4.1.2 : Acetyl-CoA + Carboxybiotin-carboxyl-carrier protein = Malonyl-CoA + Biotin-carboxyl-carrier protein
[Fig] EC 2.3.1.114 : Malonyl-CoA + 3,4-Dichloroaniline = CoA + N-(3,4-Dichlorophenyl)-malonamate
[Fig] EC 1.2.1.18 : 3-Oxopropanoate + CoA + NADP+ = Malonyl-CoA + NADPH
[Fig] EC 6.4.1.2 : ATP + Acetyl-CoA + Acid carbonate = ADP + Orthophosphate + Malonyl-CoA
[Fig] EC 2.8.3.3 : Acetyl-CoA + Malonate = Acetate + Malonyl-CoA

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.