GREP C00073

Selected compound(s)

C00073 L-Methionine

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.4.1.- : L-Methionine + H2O + NAD+ = 4-Methylthio-2-oxobutanoate + NADH + Ammonia
[Fig] 1.4.1.- : L-Methionine + H2O + NAD+ = 4-Methylthio-2-oxobutanoate + NADH + Ammonia + H+
[Fig] 1.4.1.- : L-Methionine + H2O + NAD+ = 4-Methylthio-2-oxobutanoate + NADH + H+ + Ammonia
[Fig] 1.4.1.- : L-Methionine + H2O + NADP+ = 4-Methylthio-2-oxobutanoate + NADPH + Ammonia
[Fig] 1.4.1.- : L-Methionine + H2O + NADP+ = 4-Methylthio-2-oxobutanoate + NADPH + Ammonia + H+
[Fig] 1.4.1.- : L-Methionine + H2O + NADP+ = 4-Methylthio-2-oxobutanoate + NADPH + H+ + Ammonia
[Fig] 1.4.1.- : L-Methionine + NAD+ + H2O = 4-Methylthio-2-oxobutanoate + Ammonia + NADH
[Fig] 1.4.1.- : L-Methionine + NAD+ + H2O = 4-Methylthio-2-oxobutanoate + Ammonia + NADH + H+
[Fig] 1.4.1.- : L-Methionine + NADP+ + H2O = 4-Methylthio-2-oxobutanoate + Ammonia + NADPH
[Fig] 1.4.1.- : L-Methionine + NADP+ + H2O = 4-Methylthio-2-oxobutanoate + Ammonia + NADPH + H+
[Fig] 1.4.3.- : L-Methionine + H2O + O2 = 4-Methylthio-2-oxobutanoate + Ammonia + H2O2
[Fig] 1.14.11.- : L-Methionine + O2 + 2-Ketoglutaric acid = L-Methionine S-oxide + CO2 + Butanedionic acid
[Fig] 1.14.13.- : L-Methionine S-oxide + H2O + NAD+ = L-Methionine + NADH + O2 + H+
[Fig] 1.14.13.- : L-Methionine S-oxide + H2O + NADP+ = L-Methionine + NADPH + O2 + H+
[Fig] 1.14.16.- : L-Methionine S-oxide + 6,7-Dihydrobiopterin + H2O = L-Methionine + 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + O2
[Fig] 1.14.17.- : L-Methionine + Vitamin C + O2 = L-Methionine S-oxide + Dehydroascorbate + H2O
[Fig] 2.1.1.- : L-Homocysteine + S-Adenosyl-L-methionine = L-Methionine + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : L-Homocysteine + S-Adenosyl-L-methionine = L-Methionine + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : L-Homocysteine + S-Adenosyl-L-methionine = L-Methionine + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.1.- : L-Homocysteine + S-Adenosyl-L-methionine = L-Methionine + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.2.- : L-Methionine + THF = 3-Methylthiopropanamine + 10-Formyl-THF
[Fig] 2.1.2.- : N-Formyl-L-methionine + THF = L-Methionine + 10-Formyl-THF
[Fig] 2.6.1.- : L-Methionine + Pyridoxal 5'-phosphate = 4-Methylthio-2-oxobutanoate + Pyridoxamine 5'-phosphate
[Fig] 2.6.1.- : 4-Methylthio-2-oxobutanoate + L-Glutamate = L-Methionine + 2-Ketoglutaric acid
[Fig] 3.2.1.- : L-Methionyl-tRNA + H2O = tRNA(Tyr) + L-Methionine
[Fig] 3.2.1.- : L-Methionyl-tRNA + H2O = tRNA(Arg) + L-Methionine
[Fig] 3.2.1.- : L-Methionyl-tRNA + H2O = tRNA(Cys) + L-Methionine
[Fig] 3.2.1.- : L-Methionyl-tRNA + H2O = tRNA(Gln) + L-Methionine
[Fig] 3.2.1.- : L-Methionyl-tRNA + H2O = tRNA(Glu) + L-Methionine
[Fig] 3.2.1.- : L-Methionyl-tRNA + H2O = tRNA(Ile) + L-Methionine
[Fig] 3.2.1.- : L-Methionyl-tRNA + H2O = tRNA(Leu) + L-Methionine
[Fig] 3.2.1.- : L-Methionyl-tRNA + H2O = tRNA(Met) + L-Methionine
[Fig] 3.2.1.- : L-Methionyl-tRNA + H2O = tRNA(Trp) + L-Methionine
[Fig] 3.2.1.- : L-Methionyl-tRNA + H2O = tRNA(Val) + L-Methionine
[Fig] 3.5.99.- : N-Formyl-L-methionine + H2O = L-Methionine + Formate
[Fig] 3.7.1.- : L-Methionine + H2O = 3-Methylthiopropanamine + Formate
[Fig] 3.13.1.- : L-Methionine + H2O = L-Homocysteine + Methanol
[Fig] 3.13.1.- : L-Methionine + H2O = L-Homocysteine + Methanol
[Fig] 4.1.1.- : 3-Methylthiopropanamine + CO2 = L-Methionine
[Fig] 5.-.-.- : L-Methionine = D-Methionine
[Fig] 6.3.4.- : N-Formyl-L-methionine + ADP + Orthophosphate = L-Methionine + Formate + ATP
[Fig] 6.4.1.- : L-Methionine + ADP + Orthophosphate = 3-Methylthiopropanamine + Formate + ATP
[Fig] 6.4.1.- : 3-Methylthiopropanamine + ATP + Acid carbonate = L-Methionine + ADP + Orthophosphate

Reported reactions

[Fig] EC 2.1.1.13 : 5-Methyltetrahydrofolate + L-Homocysteine = THF + L-Methionine
[Fig] EC 6.1.1.10 : ATP + L-Methionine + tRNA(Met) = 5'-AMP + Diphosphate + L-Methionyl-tRNA
[Fig] EC 2.5.1.6 : Orthophosphate + Diphosphate + S-Adenosyl-L-methionine = ATP + L-Methionine + H2O
[Fig] EC 1.4.3.2 : L-Methionine + H2O + O2 = 4-Methylthio-2-oxobutanoate + Ammonia + H2O2
[Fig] EC 2.1.1.3 : Dimethylsulfonioacetate + L-Homocysteine = (Methylthio)acetic acid + L-Methionine
[Fig] EC 2.1.1.12 : S-Adenosyl-L-methionine + L-Methionine = S-Adenosyl-L-homocysteine + S-Methyl-L-methionine
[Fig] EC 2.1.1.14 : 5-Methyltetrahydropteroyltri-L-glutamate + L-Homocysteine = Tetrahydropteroyltri-L-glutamate + L-Methionine
[Fig] EC 1.3.99.22 : Coproporphyrinogen III + 2 S-Adenosyl-L-methionine = Protoporphyrinogen IX + 2 CO2 + 2 L-Methionine + 2 5'-Deoxyadenosine
[Fig] EC 1.8.4.5 : L-Methionine + Oxidized thioredoxin + H2O = L-Methionine S-oxide + Reduced thioredoxin
[Fig] EC 2.1.1.5 : Betaine + L-Homocysteine = Dimethylglycine + L-Methionine
[Fig] EC 2.1.1.10 : S-Adenosyl-L-methionine + L-Homocysteine = S-Adenosyl-L-homocysteine + L-Methionine
[Fig] EC 2.5.1.49 : O-Acetyl-L-homoserine + Methanethiol = L-Methionine + Acetate
[Fig] EC 2.6.1.73 : L-Methionine + Glyoxalate = 4-Methylthio-2-oxobutanoate + Glycine
[Fig] EC 3.5.1.31 : N-Formyl-L-methionine + H2O = Formate + L-Methionine
[Fig] EC 4.4.1.11 : L-Methionine + H2O = Methanethiol + Ammonia + 2-Ketobutyric acid
[Fig] EC 5.1.1.2 : L-Methionine = D-Methionine
[Fig] EC 4.1.1.57 : L-Methionine = 3-Methylthiopropanamine + CO2
[Fig] EC 3.4.13.12 : Aminoacyl-L-methionine + H2O = L-Methionine

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.