GREP C00049

Selected compound(s)

C00049 2-Aminosuccinic acid

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 2-Amino-4-hydroxybutyric acid + H2O + 2 NAD+ = 2-Aminosuccinic acid + 2 NADH + 2 H+
[Fig] 1.1.1.- : 2-Amino-4-hydroxybutyric acid + H2O + 2 NADP+ = 2-Aminosuccinic acid + 2 NADPH + 2 H+
[Fig] 1.1.1.- : 2-Amino-4-hydroxybutyric acid + H2O + NAD+ = 2-Aminosuccinic acid + NADH + H+
[Fig] 1.1.1.- : 2-Amino-4-hydroxybutyric acid + H2O + NADP+ = 2-Aminosuccinic acid + NADPH + H+
[Fig] 1.1.4.- : 2-Amino-4-hydroxybutyric acid + H2O + Oxidized dithiothreitol = 2-Aminosuccinic acid + 1,4-Dithiothreitol
[Fig] 1.2.1.- : Aspartate beta-semialdehyde + H2O + NAD+ = 2-Aminosuccinic acid + NADH + H+
[Fig] 1.2.1.- : Aspartate beta-semialdehyde + H2O + NADP+ = 2-Aminosuccinic acid + NADPH + H+
[Fig] 1.2.3.- : Aspartate beta-semialdehyde + H2O + O2 = 2-Aminosuccinic acid + H2O2
[Fig] 1.4.1.- : 2-Aminosuccinic acid + H2O + NAD+ = keto-Oxaloacetate + NADH + Ammonia
[Fig] 1.4.1.- : 2-Aminosuccinic acid + H2O + NAD+ = keto-Oxaloacetate + NADH + Ammonia + H+
[Fig] 1.4.1.- : 2-Aminosuccinic acid + H2O + NAD+ = keto-Oxaloacetate + NADH + H+ + Ammonia
[Fig] 1.4.1.- : 2-Aminosuccinic acid + H2O + NAD+ = 2-Hydroxybut-2-enedioic acid + NADH + Ammonia
[Fig] 1.4.1.- : 2-Aminosuccinic acid + H2O + NAD+ = 2-Hydroxybut-2-enedioic acid + NADH + H+ + Ammonia
[Fig] 1.4.1.- : 2-Aminosuccinic acid + H2O + NADP+ = keto-Oxaloacetate + NADPH + Ammonia
[Fig] 1.4.1.- : 2-Aminosuccinic acid + H2O + NADP+ = keto-Oxaloacetate + NADPH + Ammonia + H+
[Fig] 1.4.1.- : 2-Aminosuccinic acid + H2O + NADP+ = keto-Oxaloacetate + NADPH + H+ + Ammonia
[Fig] 1.4.1.- : 2-Aminosuccinic acid + NAD+ + H2O = keto-Oxaloacetate + Ammonia + NADH
[Fig] 1.4.1.- : 2-Aminosuccinic acid + NAD+ + H2O = keto-Oxaloacetate + Ammonia + NADH + H+
[Fig] 1.4.1.- : 2-Aminosuccinic acid + NAD+ + H2O = 2-Hydroxybut-2-enedioic acid + Ammonia + NADH + H+
[Fig] 1.4.1.- : 2-Aminosuccinic acid + NADP+ + H2O = keto-Oxaloacetate + Ammonia + NADPH
[Fig] 1.4.1.- : 2-Aminosuccinic acid + NADP+ + H2O = keto-Oxaloacetate + Ammonia + NADPH + H+
[Fig] 1.4.1.- : 2-Aminosuccinic acid + NADP+ + H2O = 2-Hydroxybut-2-enedioic acid + Ammonia + NADPH
[Fig] 1.4.1.- : 2-Aminosuccinic acid + NADP+ + H2O = 2-Hydroxybut-2-enedioic acid + Ammonia + NADPH + H+
[Fig] 1.4.3.- : 2-Aminosuccinic acid + H2O + O2 = keto-Oxaloacetate + Ammonia + H2O2
[Fig] 1.4.3.- : 2-Aminosuccinic acid + H2O + O2 = 2-Hydroxybut-2-enedioic acid + Ammonia + H2O2
[Fig] 1.5.1.- : 2-Aminosuccinic acid + NAD+ = Iminoaspartate + NADH + H+
[Fig] 1.5.1.- : Iminoaspartate + NADPH + H+ = 2-Aminosuccinic acid + NADP+
[Fig] 1.5.4.- : Iminoaspartate + 1,4-Dithiothreitol = 2-Aminosuccinic acid + Oxidized dithiothreitol
[Fig] 1.5.5.- : Iminoaspartate + CoQH2 = 2-Aminosuccinic acid + CoQ
[Fig] 1.5.99.- : 2-Aminosuccinic acid + FAD = Iminoaspartate + FADH2
[Fig] 1.5.99.- : 2-Aminosuccinic acid + Coenzyme F420 = Iminoaspartate + Reduced coenzyme F420
[Fig] 1.14.11.- : 2-Aminosuccinic acid + O2 + 2-Ketoglutaric acid = erythro-3-Hydroxy-L-aspartate + CO2 + Butanedionic acid
[Fig] 1.14.11.- : 2-Aminosuccinic acid + O2 + 2-Ketoglutaric acid = L-threo-3-Hydroxyaspartate + CO2 + Butanedionic acid
[Fig] 2.1.1.- : 2-Aminosuccinic acid + S-Adenosyl-L-methionine = L-threo-3-Methylaspartate + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : 2-Aminosuccinic acid + S-Adenosyl-L-methionine = L-threo-3-Methylaspartate + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.1.- : 2-Aminosuccinic acid + S-Adenosyl-L-methionine = N-Methyl-D-aspartate + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : 2-Aminosuccinic acid + S-Adenosyl-L-methionine = N-Methyl-D-aspartate + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.2.- : 2-Aminosuccinic acid + THF = L-Alanine + 10-Formyl-THF
[Fig] 2.1.2.- : 2-Aminosuccinic acid + THF = beta-Alanine + 10-Formyl-THF
[Fig] 2.1.2.- : 2-Aminosuccinic acid + THF = D-Alanine + 10-Formyl-THF
[Fig] 2.1.2.- : 2-Aminosuccinic acid + THF = 2-Aminopropanoic acid + 10-Formyl-THF
[Fig] 2.1.2.- : N-Formyl-L-aspartate + THF = 2-Aminosuccinic acid + 10-Formyl-THF
[Fig] 2.1.3.- : N-Carbamoyl-L-aspartate + Orthophosphate = 2-Aminosuccinic acid + Carbamoyl phosphate
[Fig] 2.1.4.- : 2-Aminosuccinic acid + L-Arginine = Guanidinosuccinic acid + (S)-2,5-Diaminopentanoate
[Fig] 2.3.1.- : 2-Aminosuccinic acid + Acetyl phosphate = N-Acetyl-L-aspartate + Orthophosphate
[Fig] 2.3.1.- : N-Acetyl-L-aspartate + CoA = 2-Aminosuccinic acid + Acetyl-CoA
[Fig] 2.3.1.- : N-Acyl-L-aspartate + CoA = 2-Aminosuccinic acid + Acetyl-CoA
[Fig] 2.3.1.- : N-Acyl-L-aspartate + CoA = 2-Aminosuccinic acid + Acyl-CoA
[Fig] 2.3.1.- : N-Acyl-D-aspartate + CoA = 2-Aminosuccinic acid + Acetyl-CoA
[Fig] 2.3.1.- : N-Acyl-D-aspartate + CoA = 2-Aminosuccinic acid + Acyl-CoA
[Fig] 2.3.2.- : (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido]succinate + Ammonia = 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + 2-Aminosuccinic acid
[Fig] 2.5.1.- : L-Argininosuccinate + Ammonia = 2-Aminosuccinic acid + L-Arginine
[Fig] 2.5.1.- : L-Argininosuccinate + Ammonia = D-Arginine + 2-Aminosuccinic acid
[Fig] 2.6.1.- : keto-Oxaloacetate + L-Glutamate = 2-Aminosuccinic acid + 2-Ketoglutaric acid
[Fig] 2.6.1.- : 2-Aminosuccinic acid + Pyridoxal 5'-phosphate = keto-Oxaloacetate + Pyridoxamine 5'-phosphate
[Fig] 2.6.1.- : 2-Hydroxybut-2-enedioic acid + L-Glutamate = 2-Aminosuccinic acid + 2-Ketoglutaric acid
[Fig] 2.7.1.- : Orthophosphate + 4-Phospho-L-aspartate = Diphosphate + 2-Aminosuccinic acid
[Fig] 2.7.1.- : 2-Aminosuccinic acid + ATP = 4-Phospho-L-aspartate + ADP
[Fig] 2.7.1.- : 2-Aminosuccinic acid + Protein L-histidine = 4-Phospho-L-aspartate + Protein N(pai)-phosphohistidine
[Fig] 3.1.1.- : N-Methyl-D-aspartate + H2O = 2-Aminosuccinic acid + Methanol
[Fig] 3.1.3.- : 4-Phospho-L-aspartate + H2O = 2-Aminosuccinic acid + Orthophosphate
[Fig] 3.2.1.- : L-Aspartyl-tRNA(Asp) + H2O = tRNA(Ala) + 2-Aminosuccinic acid
[Fig] 3.2.1.- : L-Aspartyl-tRNA(Asp) + H2O = tRNA(Asp) + 2-Aminosuccinic acid
[Fig] 3.2.1.- : Asp-tRNA(Asn) + H2O = tRNA(Asn) + 2-Aminosuccinic acid
[Fig] 3.3.2.- : L-threo-3-Methylaspartate + H2O = 2-Aminosuccinic acid + Methanol
[Fig] 3.5.1.- : L-Asparagine + H2O = 2-Aminosuccinic acid + Ammonia
[Fig] 3.5.1.- : N-Carbamoyl-L-aspartate + H2O = 2-Aminosuccinic acid + CO2 + Ammonia
[Fig] 3.5.1.- : N-Acetyl-L-aspartate + H2O = 2-Aminosuccinic acid + Acetate
[Fig] 3.5.1.- : D-Asparagine + H2O = 2-Aminosuccinic acid + Ammonia
[Fig] 3.5.1.- : N-Acyl-L-aspartate + H2O = 2-Aminosuccinic acid + Acetate
[Fig] 3.5.1.- : N-Acyl-L-aspartate + H2O = 2-Aminosuccinic acid + Carboxylate
[Fig] 3.5.1.- : N-Acyl-L-aspartate + H2O = 2-Aminosuccinic acid + Fatty acid
[Fig] 3.5.1.- : 1-beta-Aspartyl-N-acetyl-D-glucosaminylamine + H2O = N-Acetyl-beta-D-glucosaminylamine + 2-Aminosuccinic acid
[Fig] 3.5.1.- : (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido]succinate + H2O = 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + 2-Aminosuccinic acid
[Fig] 3.5.1.- : N-Acyl-D-aspartate + H2O = 2-Aminosuccinic acid + Acetate
[Fig] 3.5.1.- : N-Acyl-D-aspartate + H2O = 2-Aminosuccinic acid + Carboxylate
[Fig] 3.5.1.- : N-Acyl-D-aspartate + H2O = 2-Aminosuccinic acid + Fatty acid
[Fig] 3.5.2.- : L-Argininosuccinate + H2O = 2-Aminosuccinic acid + 2-Amino-5-ureidovaleric acid
[Fig] 3.5.3.- : Guanidinosuccinic acid + H2O = 2-Aminosuccinic acid + Carbamide
[Fig] 3.5.99.- : 2-Aminosuccinic acid + H2O = L-Malate + Ammonia
[Fig] 3.5.99.- : 2-Aminosuccinic acid + H2O = (R)-Malate + Ammonia
[Fig] 3.5.99.- : 2-Aminosuccinic acid + H2O = 2-Hydroxybutanedioic acid + Ammonia
[Fig] 3.5.99.- : 2-Aminosuccinic acid + H2O = 2-Hydroxydicarboxylic acid + Ammonia
[Fig] 3.5.99.- : N-Formyl-L-aspartate + H2O = 2-Aminosuccinic acid + Formate
[Fig] 3.6.1.- : 4-Phospho-L-aspartate + H2O = Orthophosphate + 2-Aminosuccinic acid
[Fig] 3.7.1.- : 2-Aminosuccinic acid + H2O = L-Alanine + Formate
[Fig] 3.7.1.- : 2-Aminosuccinic acid + H2O = beta-Alanine + Formate
[Fig] 3.7.1.- : 2-Aminosuccinic acid + H2O = D-Alanine + Formate
[Fig] 3.7.1.- : 2-Aminosuccinic acid + H2O = 2-Aminopropanoic acid + Formate
[Fig] 4.1.1.- : L-Alanine + CO2 = 2-Aminosuccinic acid
[Fig] 4.1.1.- : beta-Alanine + CO2 = 2-Aminosuccinic acid
[Fig] 4.1.1.- : D-Alanine + CO2 = 2-Aminosuccinic acid
[Fig] 4.1.1.- : 2-Aminopropanoic acid + CO2 = 2-Aminosuccinic acid
[Fig] 4.3.1.- : Fumarate + Ammonia = 2-Aminosuccinic acid
[Fig] 4.3.1.- : Maleate + Ammonia = 2-Aminosuccinic acid
[Fig] 4.3.99.- : 2-Aminosuccinic acid + HCN = N-Formimidoyl-L-aspartate
[Fig] 5.-.-.- : 2-Aminosuccinic acid = D-Aspartate
[Fig] 6.3.1.- : N-Acetyl-beta-D-glucosaminylamine + 2-Aminosuccinic acid + ATP = 1-beta-Aspartyl-N-acetyl-D-glucosaminylamine + ADP + Orthophosphate
[Fig] 6.3.1.- : N-Acetyl-beta-D-glucosaminylamine + 2-Aminosuccinic acid + ATP = 1-beta-Aspartyl-N-acetyl-D-glucosaminylamine + Diphosphate + 5'-AMP
[Fig] 6.3.1.- : 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + 2-Aminosuccinic acid + ATP = (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido]succinate + ADP + Orthophosphate
[Fig] 6.3.1.- : 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + 2-Aminosuccinic acid + ATP = (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido]succinate + Diphosphate + 5'-AMP
[Fig] 6.3.4.- : 2-Aminosuccinic acid + ATP + Ammonia = L-Asparagine + ADP + Orthophosphate
[Fig] 6.3.4.- : 2-Aminosuccinic acid + ATP + Ammonia = L-Asparagine + Diphosphate + 5'-AMP
[Fig] 6.3.4.- : 2-Aminosuccinic acid + ATP + Ammonia = D-Asparagine + ADP + Orthophosphate
[Fig] 6.3.4.- : 2-Aminosuccinic acid + ATP + Ammonia = D-Asparagine + Diphosphate + 5'-AMP
[Fig] 6.3.4.- : 2-Aminosuccinic acid + 2-Amino-5-ureidovaleric acid + ATP = L-Argininosuccinate + ADP + Orthophosphate
[Fig] 6.3.4.- : L-Malate + ATP + Ammonia = 2-Aminosuccinic acid + ADP + Orthophosphate
[Fig] 6.3.4.- : L-Malate + ATP + Ammonia = 2-Aminosuccinic acid + Diphosphate + 5'-AMP
[Fig] 6.3.4.- : (R)-Malate + ATP + Ammonia = 2-Aminosuccinic acid + ADP + Orthophosphate
[Fig] 6.3.4.- : (R)-Malate + ATP + Ammonia = 2-Aminosuccinic acid + Diphosphate + 5'-AMP
[Fig] 6.3.4.- : 2-Hydroxybutanedioic acid + ATP + Ammonia = 2-Aminosuccinic acid + ADP + Orthophosphate
[Fig] 6.3.4.- : 2-Hydroxybutanedioic acid + ATP + Ammonia = 2-Aminosuccinic acid + Diphosphate + 5'-AMP
[Fig] 6.3.4.- : N-Formyl-L-aspartate + ADP + Orthophosphate = 2-Aminosuccinic acid + Formate + ATP
[Fig] 6.3.4.- : 2-Hydroxydicarboxylic acid + ATP + Ammonia = 2-Aminosuccinic acid + ADP + Orthophosphate
[Fig] 6.3.4.- : 2-Hydroxydicarboxylic acid + ATP + Ammonia = 2-Aminosuccinic acid + Diphosphate + 5'-AMP
[Fig] 6.3.4.- : Betalamic acid + 2-Aminosuccinic acid + ATP = Miraxanthin-II + ADP + Orthophosphate
[Fig] 6.4.1.- : L-Alanine + ATP + Acid carbonate = 2-Aminosuccinic acid + ADP + Orthophosphate
[Fig] 6.4.1.- : 2-Aminosuccinic acid + ADP + Orthophosphate = L-Alanine + Formate + ATP
[Fig] 6.4.1.- : 2-Aminosuccinic acid + ADP + Orthophosphate = beta-Alanine + Formate + ATP
[Fig] 6.4.1.- : 2-Aminosuccinic acid + ADP + Orthophosphate = D-Alanine + Formate + ATP
[Fig] 6.4.1.- : 2-Aminosuccinic acid + ADP + Orthophosphate = 2-Aminopropanoic acid + Formate + ATP
[Fig] 6.4.1.- : beta-Alanine + ATP + Acid carbonate = 2-Aminosuccinic acid + ADP + Orthophosphate
[Fig] 6.4.1.- : D-Alanine + ATP + Acid carbonate = 2-Aminosuccinic acid + ADP + Orthophosphate
[Fig] 6.4.1.- : 2-Aminopropanoic acid + ATP + Acid carbonate = 2-Aminosuccinic acid + ADP + Orthophosphate

Reported reactions

[Fig] EC 2.1.3.2 : Carbamoyl phosphate + 2-Aminosuccinic acid = Orthophosphate + N-Carbamoyl-L-aspartate
[Fig] EC 6.3.4.4 : GTP + IMP + 2-Aminosuccinic acid = GDP + Orthophosphate + Adenylosuccinate
[Fig] EC 6.1.1.12 : tRNA(Asp) + 2-Aminosuccinic acid + ATP = L-Aspartyl-tRNA(Asp) + Diphosphate + 5'-AMP
[Fig] EC 6.3.4.5 : ATP + 2-Amino-5-ureidovaleric acid + 2-Aminosuccinic acid = 5'-AMP + Diphosphate + L-Argininosuccinate
[Fig] EC 2.6.1.57 : keto-Oxaloacetate + L-Arogenate = 2-Aminosuccinic acid + Prephenate
[Fig] EC 2.6.1.31 : PM + keto-Oxaloacetate = Pyridoxal + 2-Aminosuccinic acid
[Fig] EC 4.1.1.12 : 2-Aminosuccinic acid = L-Alanine + CO2
[Fig] EC 2.7.2.4 : ATP + 2-Aminosuccinic acid = ADP + 4-Phospho-L-aspartate
[Fig] EC 1.4.3.16 : 2-Aminosuccinic acid + O2 = Iminoaspartate + H2O2
[Fig] EC 6.3.1.4 : ATP + 2-Aminosuccinic acid + Ammonia = ADP + Orthophosphate + L-Asparagine
[Fig] EC 6.3.1.1 : ATP + 2-Aminosuccinic acid + Ammonia = 5'-AMP + Diphosphate + L-Asparagine
[Fig] EC 3.5.1.7 : N-Carbamoyl-L-aspartate + H2O = 2-Aminosuccinic acid + CO2 + Ammonia
[Fig] EC 3.5.1.1 : L-Asparagine + H2O = 2-Aminosuccinic acid + Ammonia
[Fig] EC 3.5.1.38 : L-Asparagine + H2O = 2-Aminosuccinic acid + Ammonia
[Fig] EC 2.6.1.35 : Glycine + keto-Oxaloacetate = Glyoxalate + 2-Aminosuccinic acid
[Fig] EC 3.5.5.4 : 3-Cyano-L-alanine + 2 H2O = 2-Aminosuccinic acid + Ammonia
[Fig] EC 2.3.1.17 : Acetyl-CoA + 2-Aminosuccinic acid = CoA + N-Acetyl-L-aspartate
[Fig] EC 3.5.1.15 : N-Acetyl-L-aspartate + H2O = Acetate + 2-Aminosuccinic acid
[Fig] EC 4.1.1.11 : 2-Aminosuccinic acid = beta-Alanine + CO2
[Fig] EC 4.1.1.15 : 2-Aminosuccinic acid = beta-Alanine + CO2
[Fig] EC 6.3.5.4 : ATP + 2-Aminosuccinic acid + L-Glutamine + H2O = 5'-AMP + Diphosphate + L-Asparagine + L-Glutamate
[Fig] EC 2.6.1.1 : 2-Aminosuccinic acid + 2-Ketoglutaric acid = keto-Oxaloacetate + L-Glutamate
[Fig] EC 1.4.3.2 : 2-Aminosuccinic acid + H2O + O2 = keto-Oxaloacetate + Ammonia + H2O2
[Fig] EC 1.4.3.16 : 2-Aminosuccinic acid + H2O + O2 = keto-Oxaloacetate + Ammonia + H2O2
[Fig] EC 3.5.3.14 : Guanidinosuccinic acid + H2O = 2-Aminosuccinic acid + Carbamide
[Fig] EC 6.3.2.6 : ATP + 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + 2-Aminosuccinic acid = ADP + Orthophosphate + (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido]succinate
[Fig] EC 2.6.1.12 : L-Alanine + keto-Oxaloacetate = 2-Oxopropanoate + 2-Aminosuccinic acid
[Fig] EC 3.5.1.26 : 1-beta-Aspartyl-N-acetyl-D-glucosaminylamine + H2O = N-Acetyl-beta-D-glucosaminylamine + 2-Aminosuccinic acid
[Fig] EC 6.1.1.12 : ATP + 2-Aminosuccinic acid + tRNA(Asn) = 5'-AMP + Diphosphate + Asp-tRNA(Asn)
[Fig] EC 3.5.1.38 : 2-Aminosuccinic acid = Fumarate + Ammonia
[Fig] EC 4.3.1.1 : 2-Aminosuccinic acid = Fumarate + Ammonia
[Fig] EC 5.1.1.13 : 2-Aminosuccinic acid = D-Aspartate
[Fig] EC 2.6.1.70 : 2-Aminosuccinic acid + Phenylpyruvate = keto-Oxaloacetate + (S)-alpha-Amino-beta-phenylpropionic acid
[Fig] EC 3.5.1.15 : N-Acyl-L-aspartate + H2O = Carboxylate + 2-Aminosuccinic acid
[Fig] EC 3.5.1.8 : N-Formyl-L-aspartate + H2O = Formate + 2-Aminosuccinic acid
[Fig] EC 3.5.1.15 : N-Formyl-L-aspartate + H2O = Formate + 2-Aminosuccinic acid

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.