GREP C00048

Selected compound(s)

C00048 Glyoxalate

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : Glyoxalate + NADPH + H+ = Glycolate + NADP+
[Fig] 1.1.1.- : Glycolate + NAD+ = Glyoxalate + NADH + H+
[Fig] 1.1.3.- : Glycolate + O2 = Glyoxalate + H2O2
[Fig] 1.1.4.- : Glyoxalate + 1,4-Dithiothreitol = Glycolate + Oxidized dithiothreitol
[Fig] 1.1.5.- : Glyoxalate + CoQH2 = Glycolate + CoQ
[Fig] 1.1.99.- : Glycolate + FAD = Glyoxalate + FADH2
[Fig] 1.1.99.- : Glycolate + Coenzyme F420 = Glyoxalate + Reduced coenzyme F420
[Fig] 1.2.1.- : Glyoxalate + H2O + NAD+ = Ethanedioic acid + NADH + H+
[Fig] 1.2.1.- : Glyoxalate + H2O + NADP+ = Ethanedioic acid + NADPH + H+
[Fig] 1.2.1.- : Glyoxalate + NADPH + CO2 = Hydroxymalonate + NADP+
[Fig] 1.2.1.- : Glyoxalate + NADPH + CO2 = 2-Hydroxymalonate + NADP+
[Fig] 1.2.1.- : Hydroxymalonate + NAD+ = Glyoxalate + NADH + CO2
[Fig] 1.2.1.- : 2-Hydroxymalonate + NAD+ = Glyoxalate + NADH + CO2
[Fig] 1.2.3.- : Glyoxalate + H2O + O2 = Ethanedioic acid + H2O2
[Fig] 1.7.1.- : Glyoxalate + L-2,3-Diaminopropanoate + NAD+ = L-alpha-Amino-beta-oxalylaminopropionic acid + NADH + H+
[Fig] 1.7.1.- : L-alpha-Amino-beta-oxalylaminopropionic acid + NADPH + H+ = Glyoxalate + L-2,3-Diaminopropanoate + NADP+
[Fig] 1.7.3.- : Glyoxalate + L-2,3-Diaminopropanoate + O2 = L-alpha-Amino-beta-oxalylaminopropionic acid + H2O2
[Fig] 1.7.4.- : L-alpha-Amino-beta-oxalylaminopropionic acid + Reduced thioredoxin = Glyoxalate + L-2,3-Diaminopropanoate + Oxidized thioredoxin
[Fig] 1.7.99.- : Glyoxalate + L-2,3-Diaminopropanoate + FAD = L-alpha-Amino-beta-oxalylaminopropionic acid + FADH2
[Fig] 1.13.11.- : 4-Hydroxybenzaldehyde + Glyoxalate = 4-Coumarate + O2
[Fig] 1.14.11.- : Rifamycin B + O2 + 2-Ketoglutaric acid = Rifamycin + Glyoxalate + CO2 + Butanedionic acid
[Fig] 1.14.11.- : 2,4-D + O2 + 2-Ketoglutaric acid = 2,4-Dichlorophenol + Glyoxalate + CO2 + Butanedionic acid
[Fig] 1.14.11.- : 4-CPA + O2 + 2-Ketoglutaric acid = Glyoxalate + 4-Chlorophenol + CO2 + Butanedionic acid
[Fig] 1.14.11.- : 2,4,5-Trichlorophenoxyacetic acid + O2 + 2-Ketoglutaric acid = 2,4,5-Trichlorophenol + Glyoxalate + CO2 + Butanedionic acid
[Fig] 2.1.1.- : Glyoxalate + S-Adenosyl-L-methionine = 2-Oxopropanoate + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : Glyoxalate + S-Adenosyl-L-methionine = 2-Oxopropanoate + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : Glyoxalate + S-Adenosyl-L-methionine = 2-Oxopropanoate + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.1.- : Glyoxalate + S-Adenosyl-L-methionine = 2-Oxopropanoate + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.2.- : Ketomalonic acid + THF = Glyoxalate + 10-Formyl-THF
[Fig] 2.3.3.- : Thiamine diphosphate + 2-Hydroxy-3-oxoadipate = Succinate semialdehyde-thiamin diphosphate anion + Glyoxalate
[Fig] 3.3.2.- : 2-Oxopropanoate + H2O = Glyoxalate + Methanol
[Fig] 3.3.2.- : 2-Oxopropanoate + H2O = Glyoxalate + Methanol
[Fig] 3.7.1.- : Ketomalonic acid + H2O = Glyoxalate + Formate
[Fig] 4.1.1.- : Glyoxalate + CO2 = Ketomalonic acid
[Fig] 4.1.2.- : Glyoxalate + Formaldehyde = Hydroxypyruvate
[Fig] 4.1.2.- : Glyoxalate + Formaldehyde = 2-Hydroxy-3-oxopropanoate
[Fig] 4.1.2.- : L-erythro-3-Methylmalyl-CoA = Propanoyl-CoA + Glyoxalate
[Fig] 4.1.2.- : L-erythro-3-Methylmalyl-CoA = Long-chain acyl-CoA + Glyoxalate
[Fig] 4.1.3.- : Glyoxalate + Acetate = L-Malate
[Fig] 4.1.3.- : Glyoxalate + Acetate = (R)-Malate
[Fig] 4.1.3.- : Glyoxalate + Acetate = 2-Hydroxybutanedioic acid
[Fig] 6.4.1.- : Glyoxalate + ATP + Acid carbonate = Ketomalonic acid + ADP + Orthophosphate
[Fig] 6.4.1.- : Ketomalonic acid + ADP + Orthophosphate = Glyoxalate + Formate + ATP

Reported reactions

[Fig] EC 2.6.1.60 : Aromatic amino acid + Glyoxalate = Aromatic oxo acid + Glycine
[Fig] EC 4.3.2.5 : Peptidylamidoglycolate = Peptidyl amide + Glyoxalate
[Fig] EC 2.6.1.63 : 3-Anthraniloyl-L-alanine + Glyoxalate = 4-(2-Aminophenyl)-2,4-dioxobutanoate + Glycine
[Fig] EC 1.4.3.19 : N-Methylglycine + H2O + O2 = Glyoxalate + Methanamine + H2O2
[Fig] EC 1.4.3.19 : N-Ethylglycine + H2O + O2 = Glyoxalate + Ethylamine + H2O2
[Fig] EC 2.6.1.4 : Glycine + 2-Ketoglutaric acid = Glyoxalate + L-Glutamate
[Fig] EC 2.6.1.35 : Glycine + keto-Oxaloacetate = Glyoxalate + 2-Aminosuccinic acid
[Fig] EC 1.1.1.79 : Glycolate + NADP+ = Glyoxalate + NADPH
[Fig] EC 1.2.3.5 : Glyoxalate + O2 + H2O = Ethanedioic acid + H2O2
[Fig] EC 1.2.1.17 : Glyoxalate + CoA + NADP+ = Oxalyl-CoA + NADPH + H+
[Fig] EC 3.5.3.19 : (-)-Ureidoglycolate + H2O = Glyoxalate + 2 Ammonia + CO2
[Fig] EC 4.3.2.3 : (-)-Ureidoglycolate = Glyoxalate + Carbamide
[Fig] EC 2.3.3.11 : 2-Hydroxyglutarate + CoA = Propanoyl-CoA + H2O + Glyoxalate
[Fig] EC 1.1.1.26 : Glycolate + NAD+ = Glyoxalate + NADH + H+
[Fig] EC 1.1.1.29 : Glycolate + NAD+ = Glyoxalate + NADH + H+
[Fig] EC 2.3.3.12 : 3-Propylmalate + CoA = Pentanoyl-CoA + H2O + Glyoxalate
[Fig] EC 2.3.3.7 : 3-Ethylmalate + CoA = Butanoyl-CoA + H2O + Glyoxalate
[Fig] EC 1.14.-.- : 2 4-CPA + O2 = 2 4-Chlorophenol + 2 Glyoxalate
[Fig] EC 1.13.99.- : 2 2,4,5-Trichlorophenoxyacetic acid + O2 = 2 2,4,5-Trichlorophenol + 2 Glyoxalate
[Fig] EC 1.14.11.- : 2,4-D + 2-Ketoglutaric acid + O2 = 2,4-Dichlorophenol + Glyoxalate + Butanedionic acid + CO2 + H2O
[Fig] EC 4.1.3.16 : 4-Hydroxy-2-oxoglutarate = 2-Oxopropanoate + Glyoxalate
[Fig] EC 4.1.1.3 : D-4-Hydroxy-2-oxoglutarate = 2-Oxopropanoate + Glyoxalate
[Fig] EC 4.1.2.14 : D-4-Hydroxy-2-oxoglutarate = 2-Oxopropanoate + Glyoxalate
[Fig] EC 4.1.3.16 : D-4-Hydroxy-2-oxoglutarate = 2-Oxopropanoate + Glyoxalate
[Fig] EC 2.3.3.9 : L-Malate + CoA = Acetyl-CoA + H2O + Glyoxalate
[Fig] EC 4.1.3.24 : (3S)-3-Carboxy-3-hydroxypropanoyl-CoA = Acetyl-CoA + Glyoxalate
[Fig] EC 2.2.1.5 : 2-Hydroxy-3-oxoadipate + CO2 = 2-Ketoglutaric acid + Glyoxalate
[Fig] EC 2.6.1.45 : L-Serine + Glyoxalate = Hydroxypyruvate + Glycine
[Fig] EC 1.1.3.15 : Glycolate + O2 = Glyoxalate + H2O2
[Fig] EC 1.1.99.14 : Glycolate + Acceptor = Glyoxalate + Reduced acceptor
[Fig] EC 1.4.2.1 : Glycine + H2O + 2 Ferricytochrome c = Glyoxalate + Ammonia + 2 Ferrocytochrome c
[Fig] EC 4.1.3.13 : 3-Oxalomalate = keto-Oxaloacetate + Glyoxalate
[Fig] EC 4.1.3.14 : erythro-3-Hydroxy-L-aspartate = Glycine + Glyoxalate
[Fig] EC 1.4.1.10 : Glycine + H2O + NAD+ = Glyoxalate + Ammonia + NADH
[Fig] EC 4.1.3.1 : 1-Hydroxypropane-1,2,3-tricarboxylic acid = Butanedionic acid + Glyoxalate
[Fig] EC 1.4.3.3 : Glycine + H2O + O2 = Glyoxalate + Ammonia + H2O2
[Fig] EC 1.4.3.19 : Glycine + H2O + O2 = Glyoxalate + Ammonia + H2O2
[Fig] EC 2.6.1.44 : L-Alanine + Glyoxalate = 2-Oxopropanoate + Glycine
[Fig] EC 4.1.1.47 : 2 Glyoxalate = 2-Hydroxy-3-oxopropanoate + CO2
[Fig] EC 2.6.1.73 : L-Methionine + Glyoxalate = 4-Methylthio-2-oxobutanoate + Glycine

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.