GREP C00047

Selected compound(s)

C00047 L-Lysine

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.4.1.- : L-Lysine + H2O + NAD+ = Allysine + NADH + Ammonia
[Fig] 1.4.1.- : L-Lysine + H2O + NAD+ = Allysine + NADH + H+ + Ammonia
[Fig] 1.4.1.- : L-Lysine + H2O + NAD+ = 2-Oxo-6-aminocaproate + NADH + Ammonia
[Fig] 1.4.1.- : L-Lysine + H2O + NAD+ = 2-Oxo-6-aminocaproate + NADH + Ammonia + H+
[Fig] 1.4.1.- : L-Lysine + H2O + NAD+ = 2-Oxo-6-aminocaproate + NADH + H+ + Ammonia
[Fig] 1.4.1.- : L-Lysine + H2O + NAD+ = 2-Aminoadipate 6-semialdehyde + NADH + Ammonia
[Fig] 1.4.1.- : L-Lysine + H2O + NAD+ = 2-Aminoadipate 6-semialdehyde + NADH + H+ + Ammonia
[Fig] 1.4.1.- : L-Lysine + H2O + NADP+ = Allysine + NADPH + Ammonia
[Fig] 1.4.1.- : L-Lysine + H2O + NADP+ = Allysine + NADPH + H+ + Ammonia
[Fig] 1.4.1.- : L-Lysine + H2O + NADP+ = 2-Oxo-6-aminocaproate + NADPH + Ammonia
[Fig] 1.4.1.- : L-Lysine + H2O + NADP+ = 2-Oxo-6-aminocaproate + NADPH + Ammonia + H+
[Fig] 1.4.1.- : L-Lysine + H2O + NADP+ = 2-Oxo-6-aminocaproate + NADPH + H+ + Ammonia
[Fig] 1.4.1.- : L-Lysine + H2O + NADP+ = 2-Aminoadipate 6-semialdehyde + NADPH + Ammonia
[Fig] 1.4.1.- : L-Lysine + H2O + NADP+ = 2-Aminoadipate 6-semialdehyde + NADPH + H+ + Ammonia
[Fig] 1.4.1.- : L-Lysine + NAD+ + H2O = Allysine + Ammonia + NADH
[Fig] 1.4.1.- : L-Lysine + NAD+ + H2O = Allysine + Ammonia + NADH + H+
[Fig] 1.4.1.- : L-Lysine + NAD+ + H2O = 2-Oxo-6-aminocaproate + Ammonia + NADH
[Fig] 1.4.1.- : L-Lysine + NAD+ + H2O = 2-Oxo-6-aminocaproate + Ammonia + NADH + H+
[Fig] 1.4.1.- : L-Lysine + NAD+ + H2O = 2-Aminoadipate 6-semialdehyde + Ammonia + NADH
[Fig] 1.4.1.- : L-Lysine + NAD+ + H2O = 2-Aminoadipate 6-semialdehyde + Ammonia + NADH + H+
[Fig] 1.4.1.- : L-Lysine + NADP+ + H2O = Allysine + Ammonia + NADPH
[Fig] 1.4.1.- : L-Lysine + NADP+ + H2O = Allysine + Ammonia + NADPH + H+
[Fig] 1.4.1.- : L-Lysine + NADP+ + H2O = 2-Oxo-6-aminocaproate + Ammonia + NADPH
[Fig] 1.4.1.- : L-Lysine + NADP+ + H2O = 2-Oxo-6-aminocaproate + Ammonia + NADPH + H+
[Fig] 1.4.1.- : L-Lysine + NADP+ + H2O = 2-Aminoadipate 6-semialdehyde + Ammonia + NADPH
[Fig] 1.4.1.- : L-Lysine + NADP+ + H2O = 2-Aminoadipate 6-semialdehyde + Ammonia + NADPH + H+
[Fig] 1.4.3.- : L-Lysine + H2O + O2 = Allysine + Ammonia + H2O2
[Fig] 1.4.3.- : L-Lysine + H2O + O2 = 2-Oxo-6-aminocaproate + Ammonia + H2O2
[Fig] 1.4.3.- : L-Lysine + H2O + O2 = 2-Aminoadipate 6-semialdehyde + Ammonia + H2O2
[Fig] 1.5.1.11 : L-Saccharopine + H2O + NAD+ = L-Lysine + 2-Ketoglutaric acid + NADH + H+
[Fig] 1.5.1.11 : D-Lysopine + H2O + NAD+ = 2-Oxopropanoate + L-Lysine + NADH + H+
[Fig] 1.14.11.- : L-Lysine + O2 + 2-Ketoglutaric acid = N6-Hydroxy-L-lysine + CO2 + Butanedionic acid
[Fig] 1.14.11.- : L-Saccharopine + O2 + 2-Ketoglutaric acid = L-Lysine + 2-Ketoglutaric acid + CO2 + Butanedionic acid
[Fig] 1.14.11.- : L-Saccharopine + Vitamin C + O2 = L-Lysine + 2-Ketoglutaric acid + Dehydroascorbate + H2O
[Fig] 1.14.11.- : D-Lysopine + O2 + 2-Ketoglutaric acid = 2-Oxopropanoate + L-Lysine + CO2 + Butanedionic acid
[Fig] 1.14.11.- : D-Lysopine + Vitamin C + O2 = 2-Oxopropanoate + L-Lysine + Dehydroascorbate + H2O
[Fig] 1.14.13.- : N6-Hydroxy-L-lysine + H2O + NAD+ = L-Lysine + NADH + O2 + H+
[Fig] 1.14.16.- : N6-Hydroxy-L-lysine + 6,7-Dihydrobiopterin + H2O = L-Lysine + 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + O2
[Fig] 1.14.17.- : L-Lysine + Vitamin C + O2 = N6-Hydroxy-L-lysine + Dehydroascorbate + H2O
[Fig] 2.1.1.- : L-Lysine + S-Adenosyl-L-methionine = N6-Methyl-L-lysine + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : L-Lysine + S-Adenosyl-L-methionine = N6-Methyl-L-lysine + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.2.- : L-Lysine + THF = 1,5-Diaminopentane + 10-Formyl-THF
[Fig] 2.1.2.- : LL-2,6-Diaminoheptanedioate + THF = L-Lysine + 10-Formyl-THF
[Fig] 2.1.2.- : meso-2,6-Diaminoheptanedioate + THF = L-Lysine + 10-Formyl-THF
[Fig] 2.1.3.- : L-Homocitrulline + Orthophosphate = L-Lysine + Carbamoyl phosphate
[Fig] 2.1.4.- : L-Lysine + L-Arginine = Homoarginine + (S)-2,5-Diaminopentanoate
[Fig] 2.3.1.- : L-Lysine + Acetyl phosphate = N6-Acetyl-L-lysine + Orthophosphate
[Fig] 2.3.1.- : L-Lysine + Acetyl phosphate = N2-Acetyl-L-lysine + Orthophosphate
[Fig] 2.3.1.- : L-Lysine + Aminoacyl-tRNA = Xaa-Lys + tRNA(Asp)
[Fig] 2.3.1.- : tRNA + Xaa-Lys = Aminoacyl-tRNA + L-Lysine
[Fig] 2.3.1.- : tRNA(Phe) + Xaa-Lys = Aminoacyl-tRNA + L-Lysine
[Fig] 2.3.1.- : N6-Acyl-L-lysine + CoA = L-Lysine + Acetyl-CoA
[Fig] 2.3.1.- : N6-Acyl-L-lysine + CoA = L-Lysine + Acyl-CoA
[Fig] 2.3.1.- : N6-Acetyl-L-lysine + CoA = L-Lysine + Acetyl-CoA
[Fig] 2.3.1.- : N2-Acetyl-L-lysine + CoA = L-Lysine + Acetyl-CoA
[Fig] 2.3.2.- : L-Lysyl-tRNA + Ammonia = L-Lysine + Alkylamine
[Fig] 2.5.1.- : L-Lysine + Methylthioadenosine + H+ = L-Alanine + (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt
[Fig] 2.5.1.- : L-Lysine + Methylthioadenosine + H+ = D-Alanine + (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt
[Fig] 2.5.1.- : L-Lysine + Methylthioadenosine + H+ = 2-Aminopropanoic acid + (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt
[Fig] 2.5.1.- : L-Lysine + Methylthioadenosine = L-Alanine + (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt
[Fig] 2.5.1.- : L-Lysine + Methylthioadenosine = D-Alanine + (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt
[Fig] 2.5.1.- : L-Lysine + Methylthioadenosine = 2-Aminopropanoic acid + (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt
[Fig] 2.5.1.- : L-Saccharopine + Ammonia = L-Lysine + L-Glutamate
[Fig] 2.5.1.- : L-Saccharopine + Ammonia = L-Lysine + D-Glutamate
[Fig] 2.6.1.- : L-Lysine + Pyridoxal 5'-phosphate = Allysine + Pyridoxamine 5'-phosphate
[Fig] 2.6.1.- : L-Lysine + Pyridoxal 5'-phosphate = 2-Oxo-6-aminocaproate + Pyridoxamine 5'-phosphate
[Fig] 2.6.1.- : L-Lysine + Pyridoxal 5'-phosphate = 2-Aminoadipate 6-semialdehyde + Pyridoxamine 5'-phosphate
[Fig] 2.6.1.- : Allysine + L-Glutamate = L-Lysine + 2-Ketoglutaric acid
[Fig] 2.6.1.- : 2-Oxo-6-aminocaproate + L-Glutamate = L-Lysine + 2-Ketoglutaric acid
[Fig] 2.6.1.- : 2-Aminoadipate 6-semialdehyde + L-Glutamate = L-Lysine + 2-Ketoglutaric acid
[Fig] 3.1.1.- : L-Lysyl-tRNA + H2O = L-Lysine + Fatty acid
[Fig] 3.1.1.- : N6-Methyl-L-lysine + H2O = L-Lysine + Methanol
[Fig] 3.5.1.- : Xaa-Lys + H2O = Amino acid + L-Lysine
[Fig] 3.5.1.- : Kallidin + H2O = Bradykinin + L-Lysine
[Fig] 3.5.1.- : L-Lysinamide + H2O = L-Lysine + Ammonia
[Fig] 3.5.1.- : L-Homocitrulline + H2O = L-Lysine + CO2 + Ammonia
[Fig] 3.5.1.- : N6-Acyl-L-lysine + H2O = L-Lysine + Acetate
[Fig] 3.5.1.- : N6-Acyl-L-lysine + H2O = L-Lysine + Carboxylate
[Fig] 3.5.1.- : N6-Acyl-L-lysine + H2O = L-Lysine + Fatty acid
[Fig] 3.5.1.- : N6-Acetyl-L-lysine + H2O = L-Lysine + Acetate
[Fig] 3.5.1.- : Peptide(Lys-, Arg-) + H2O = Peptide + L-Lysine
[Fig] 3.5.1.- : N6-[(Indole-3-yl)acetyl]-L-lysine + H2O = L-Lysine + Indole-3-acetate
[Fig] 3.5.1.- : Biocytin + H2O = Biotin + L-Lysine
[Fig] 3.5.1.- : UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + H2O = UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + L-Lysine
[Fig] 3.5.1.- : N2-Acetyl-L-lysine + H2O = L-Lysine + Acetate
[Fig] 3.5.3.- : Homoarginine + H2O = L-Lysine + Carbamide
[Fig] 3.7.1.- : L-Lysine + H2O = 1,5-Diaminopentane + Formate
[Fig] 3.7.1.- : LL-2,6-Diaminoheptanedioate + H2O = L-Lysine + Formate
[Fig] 3.7.1.- : meso-2,6-Diaminoheptanedioate + H2O = L-Lysine + Formate
[Fig] 4.1.1.- : L-Lysine + CO2 = LL-2,6-Diaminoheptanedioate
[Fig] 4.1.1.- : L-Lysine + CO2 = meso-2,6-Diaminoheptanedioate
[Fig] 4.1.1.- : 1,5-Diaminopentane + CO2 = L-Lysine
[Fig] 4.3.1.- : 2-Piperidinecarboxylic acid + Ammonia = L-Lysine
[Fig] 5.-.-.- : L-Lysine = D-2,6-Diaminohexanoic acid
[Fig] 5.4.3.- : 2,5-Diaminohexanoate = L-Lysine
[Fig] 6.3.1.- : Peptide + L-Lysine + ATP = Peptide(Lys-, Arg-) + ADP + Orthophosphate
[Fig] 6.3.1.- : Peptide + L-Lysine + ATP = Peptide(Lys-, Arg-) + Diphosphate + 5'-AMP
[Fig] 6.3.1.- : Amino acid + L-Lysine + ATP = Xaa-Lys + ADP + Orthophosphate
[Fig] 6.3.1.- : Amino acid + L-Lysine + ATP = Xaa-Lys + Diphosphate + 5'-AMP
[Fig] 6.3.1.- : L-Lysine + Indole-3-acetate + ATP = N6-[(Indole-3-yl)acetyl]-L-lysine + ADP + Orthophosphate
[Fig] 6.3.1.- : L-Lysine + Indole-3-acetate + ATP = N6-[(Indole-3-yl)acetyl]-L-lysine + Diphosphate + 5'-AMP
[Fig] 6.3.1.- : Biotin + L-Lysine + ATP = Biocytin + ADP + Orthophosphate
[Fig] 6.3.1.- : Biotin + L-Lysine + ATP = Biocytin + Diphosphate + 5'-AMP
[Fig] 6.3.1.- : Bradykinin + L-Lysine + ATP = Kallidin + ADP + Orthophosphate
[Fig] 6.3.1.- : Bradykinin + L-Lysine + ATP = Kallidin + Diphosphate + 5'-AMP
[Fig] 6.3.1.- : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + L-Lysine + ATP = UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + ADP + Orthophosphate
[Fig] 6.3.1.- : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + L-Lysine + ATP = UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + Diphosphate + 5'-AMP
[Fig] 6.3.4.- : L-Lysine + ATP + Ammonia = L-Lysinamide + ADP + Orthophosphate
[Fig] 6.3.4.- : L-Lysine + ATP + Ammonia = L-Lysinamide + Diphosphate + 5'-AMP
[Fig] 6.4.1.- : L-Lysine + ATP + Acid carbonate = LL-2,6-Diaminoheptanedioate + ADP + Orthophosphate
[Fig] 6.4.1.- : L-Lysine + ATP + Acid carbonate = meso-2,6-Diaminoheptanedioate + ADP + Orthophosphate
[Fig] 6.4.1.- : L-Lysine + ADP + Orthophosphate = 1,5-Diaminopentane + Formate + ATP
[Fig] 6.4.1.- : LL-2,6-Diaminoheptanedioate + ADP + Orthophosphate = L-Lysine + Formate + ATP
[Fig] 6.4.1.- : meso-2,6-Diaminoheptanedioate + ADP + Orthophosphate = L-Lysine + Formate + ATP
[Fig] 6.4.1.- : 1,5-Diaminopentane + ATP + Acid carbonate = L-Lysine + ADP + Orthophosphate

Reported reactions

[Fig] EC 1.5.3.4 : N6-Methyl-L-lysine + H2O + O2 = L-Lysine + Formaldehyde + H2O2
[Fig] EC 6.3.2.20 : ATP + Indole-3-acetate + L-Lysine = ADP + Orthophosphate + N6-[(Indole-3-yl)acetyl]-L-lysine
[Fig] EC 3.5.1.- : N2-Acetyl-L-lysine + H2O = L-Lysine + Acetate
[Fig] EC 2.1.3.8 : Carbamoyl phosphate + L-Lysine = Orthophosphate + L-Homocitrulline
[Fig] EC 6.1.1.6 : ATP + L-Lysine + tRNA(Lys) = 5'-AMP + Diphosphate + L-Lysyl-tRNA
[Fig] EC 2.3.1.32 : Acetyl phosphate + L-Lysine = Orthophosphate + N6-Acetyl-L-lysine
[Fig] EC 6.3.2.7 : ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + L-Lysine = ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine
[Fig] EC 6.3.2.7 : ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + L-Lysine = ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine
[Fig] EC 5.1.1.5 : L-Lysine = D-2,6-Diaminohexanoic acid
[Fig] EC 5.1.1.9 : L-Lysine = D-2,6-Diaminohexanoic acid
[Fig] EC 5.4.3.2 : L-Lysine = (3S)-3,6-Diaminohexanoate
[Fig] EC 4.1.1.18 : L-Lysine = 1,5-Diaminopentane + CO2
[Fig] EC 3.5.2.11 : L-Lysine 1,6-lactam + H2O = L-Lysine
[Fig] EC 1.4.1.15 : L-Lysine + NAD+ = 1,2-Didehydropiperidine-2-carboxylate + Ammonia + NADH
[Fig] EC 1.4.1.18 : L-Lysine + NAD+ + H2O = Allysine + NADH + Ammonia + H+
[Fig] EC 1.4.3.14 : L-Lysine + O2 + H2O = 2-Oxo-6-aminocaproate + Ammonia + H2O2
[Fig] EC 1.14.13.59 : L-Lysine + O2 + NADPH = N6-Hydroxy-L-lysine + NADP+ + H2O
[Fig] EC 1.13.12.2 : L-Lysine + O2 = 5-Aminopentanamide + CO2 + H2O
[Fig] EC 1.5.1.7 : L-Saccharopine + NAD+ + H2O = L-Lysine + 2-Ketoglutaric acid + NADH + H+
[Fig] EC 1.5.1.8 : L-Saccharopine + NADP+ + H2O = L-Lysine + 2-Ketoglutaric acid + NADPH + H+
[Fig] EC 6.3.2.11 : ATP + L-Lysine + beta-Alanine = 5'-AMP + Diphosphate + beta-Alanyl-L-lysine
[Fig] EC 3.4.13.4 : beta-Alanyl-L-lysine + H2O = beta-Alanine + L-Lysine
[Fig] EC 3.5.1.12 : Biocytin + H2O = Biotin + L-Lysine
[Fig] EC 4.1.1.20 : meso-2,6-Diaminoheptanedioate = L-Lysine + CO2
[Fig] EC 1.5.1.16 : D-Lysopine + NADP+ + H2O = L-Lysine + 2-Oxopropanoate + NADPH
[Fig] EC 2.6.1.71 : L-Lysine + 2-Oxopropanoate = 2-Aminoadipate 6-semialdehyde + L-Alanine
[Fig] EC 2.3.1.- : L-Lysine + Acetyl-CoA = N6-Acetyl-L-lysine + CoA
[Fig] EC 2.6.1.36 : L-Lysine + 2-Ketoglutaric acid = 2-Aminoadipate 6-semialdehyde + L-Glutamate
[Fig] EC 3.5.1.17 : N6-Acetyl-L-lysine + H2O = Acetate + L-Lysine
[Fig] EC 3.5.1.17 : N6-Acyl-L-lysine + H2O = Carboxylate + L-Lysine

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.